ArticleJournal of neurology, neurosurgery, and psychiatry2001
Spinal cord magnetic resonance imaging demonstrates sensory neuronal involvement and clinical severity in neuronopathy associated with Sjögren's syndrome.
Article in Journal of neurology, neurosurgery, and psychiatry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Recommendations on neurologic, cognitive, and psychiatric manifestations in patients with Sjögren's disease by the Brazilian Society of Rheumatology.Advances in rheumatology (London, England) · 2025Guideline
- Retrospective Review of 56 Patients with Sensory Ganglionopathy.Noro psikiyatri arsivi · 2026Article
- Neurological and Inflammatory Manifestations in Sjögren's Syndrome: The Role of the Kynurenine Metabolic Pathway.International journal of molecular sciences · 2018Review
- Neurological Complications of Sjögren's Syndrome: Diagnosis and Management.Current treatment options in rheumatology · 2017Article
- Article
- Unusual presentation of Sjögren's syndrome.BMJ case reports · 2014Article
- MRI of the spinal tuberculoma, paravertebral tubercular abscess and pulmonary tuberculosis.BMJ case reports · 2013Article
- Sensory neuronopathy involves the spinal cord and brachial plexus: a quantitative study employing multiple-echo data image combination (MEDIC) and turbo inversion recovery magnitude (TIRM).Neuroradiology · 2013Article
- Sensory neuronopathy and autoimmune diseases.Autoimmune diseases · 2012Article
- Posterior column involvement in Miller Fisher syndrome or dorsal root ganglion neuronopathy?AJNR. American journal of neuroradiology · 2005Article
- Magnetic Resonance Imaging Findings in a Dog with Sensory Neuronopathy.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine spinal cord MRI findings in neuronopathy associated with Sjögren's syndrome and their correlation with severity of sensory impairment.
methodsClinical and electrophysiological features, pathological findings in the sural nerve, and hyperintensity on T2* weighted MRI in the spinal dorsal columns were evaluated in 14 patients with neuronopathy associated with Sjögren's syndrome.
resultsOf 14 patients, 12 showed high intensity by T2* weighted MRI in the posterior columns of the cervical cord. High intensity areas were seen in both the fasciculus cuneatus and gracilis in nine patients, who showed severe and widespread sensory deficits in the limbs and trunk; these patients also had a high frequency of autonomic symptoms. Somatosensory evoked potentials often could not be elicited. Hyperintensity restricted to the fasciculus gracilis was seen in three patients, who showed sensory deficits restricted to lower limbs without trunk involvement, or with only partial limb involvement; no autonomic symptoms were noted. The two patients who did not show high intensity areas in the dorsal columns showed restricted sensory involvement in the limbs. All patients showed axonal loss predominantly affecting large fibres, without axonal sprouting.
conclusionsHigh intensity areas on T2* weighted MRI in the spinal dorsal columns reflect the degree of sensory neuronal involvement in neuronopathy associated with Sjögren's syndrome; this finding could also be a helpful marker for estimating severity of this neuronopathy.
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