ArticleAntimicrobial agents and chemotherapy2001
Pharmacokinetics of levofloxacin and ciprofloxacin during continuous renal replacement therapy in critically ill patients.
Article in Antimicrobial agents and chemotherapy, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics.Critical care (London, England) · 2015Trial
- An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration.BMC clinical pharmacology · 2011Trial
- Pharmacokinetics and pharmacodynamics of imipenem during continuous renal replacement therapy in critically ill patients.Antimicrobial agents and chemotherapy · 2005Trial
- Early Oral Antibiotic Switch in Staphylococcus aureus Bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Key Factors in Effective Patient-Tailored Dosing of Fluoroquinolones in Urological Infections: Interindividual Pharmacokinetic and Pharmacodynamic Variability.Antibiotics (Basel, Switzerland) · 2022Review
- Comparison of adsorption of selected antibiotics on the filters in continuous renal replacement therapy circuits: in vitro studies.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2020Article
- Pharmacokinetics of ciprofloxacin during continuous renal replacement therapy in intensive care patients - new assessment.Anaesthesiology intensive therapy · 2020Article
- Recommendation of Antimicrobial Dosing Optimization During Continuous Renal Replacement Therapy.Frontiers in pharmacology · 2020Review
- A Guide to Understanding Antimicrobial Drug Dosing in Critically Ill Patients on Renal Replacement Therapy.Antimicrobial agents and chemotherapy · 2019Review
- Presence and accuracy of drug dosage recommendations for continuous renal replacement therapy in tertiary drug information references.The Canadian journal of hospital pharmacy · 2012Article
- Antibiotic dosing in critically ill patients with acute kidney injury.Nature reviews. Nephrology · 2011Review
- Cumulative clinical experience from over a decade of use of levofloxacin in urinary tract infections: critical appraisal and role in therapy.Infection and drug resistance · 2011Article
- Dosing Recommendations for Continuous Venovenous Hemodiafiltration with AN69 Filter Membranes and Prismaflex Dialyzers.The Canadian journal of hospital pharmacy · 2009Article
- Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy.Clinical pharmacokinetics · 2007Review
- Discrepancies between observed and predicted continuous venovenous hemofiltration removal of antimicrobial agents in critically ill patients and the effects on dosing.Intensive care medicine · 2006Article
- Levofloxacin: a review of its use in the treatment of bacterial infections in the United States.Drugs · 2003Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pharmacokinetics of intravenously administered levofloxacin and ciprofloxacin were studied in intensive care unit patients during continuous venovenous hemofiltration (CVVH; four patients received levofloxacin, and five received ciprofloxacin) or hemodiafiltration (CVVHDF; six patients received levofloxacin, and five received ciprofloxacin). Levofloxacin clearance was substantially increased during both CVVH and CVVHDF, while ciprofloxacin clearance was affected less. The results of this study suggest that doses of levofloxacin of 250 mg/day and ciprofloxacin of 400 mg/day are sufficient to maintain effective drug concentrations in the plasma of patients undergoing CVVH or CVVHDF.
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