Evidence map›Paper›PMID 11555537›Full record

ReviewChest2001

Lipid disorders: justification of methods and goals of treatment.

J B Braunstein, A Cheng, G Cohn, M Aggarwal, C M Nass, R S Blumenthal

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Chest, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00795912 (A Study Of The Usage Of Statins In A Community Heart Failure Population), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00795912 phase4completedstarted 2003, after this paper: background citation

A Study Of The Usage Of Statins In A Community Heart Failure Population: The Impact of HMG Co-Enzyme A Reductase Inhibitors on Heart Structural Parameters, Brain Naturetic Peptide, Markers of Inflammation and Fibrosis

Ran2003Enrolled56Registered outcomes2Posted comparisons0ConditionsHeart FailureArmsAtorvastatin
Open the trial in the graph
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

J B BraunsteinCiccarone Center for the Prevention of Heart Disease, Division of Cardiology, Department of Internal Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
A Cheng
G Cohn
M Aggarwal
C M Nass
R S Blumenthal
Johns Hopkins Hospital · USCleveland Clinic Florida · USTufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyslipidemia is a major risk factor for coronary heart disease (CHD). While some uncertainty exists about the clinical significance of improving high-density lipoprotein cholesterol and triglyceride levels, large primary- and secondary-prevention studies aimed at lowering low-density lipoprotein cholesterol levels with statins have convincingly reduced CHD events and total mortality. Despite the strong clinical evidence and widely publicized treatment guidelines, many hyperlipidemic patients receive inadequate lipid-lowering treatment. This failure to achieve clinical treatment goals may be due to poor physician adherence to treatment guidelines, patient noncompliance, and the presence of concomitant medical conditions that modify typical hyperlipidemia management. This review considers the challenges and available strategies to optimize lipid management in patients at risk for CHD.

Indexed as

AdultCholesterol, HDLCholesterol, LDLCoronary DiseaseDiabetic AngiopathiesFemaleGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemiasHypertensionHypolipidemic AgentsMaleMiddle AgedPatient CompliancePostmenopauseCholesterol, HDLCholesterol, LDLHydroxymethylglutaryl-CoA Reductase InhibitorsHypolipidemic AgentsTriglycerides

Identifiers

PMID11555537
OpenAlexW2008224494

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.