ArticleProceedings of the National Academy of Sciences of the United States of America2001
Molecular synapomorphies resolve evolutionary relationships of extant jawed vertebrates.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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47 citing papers in PubMed.
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- Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS.Molecular therapy. Nucleic acids · 2018Article
- Resolving the Phylogenetic Position of Coelacanth: The Closest Relative Is Not Always the Most Appropriate Outgroup.Genome biology and evolution · 2016Article
- Tc1-like Transposase Thm3 of Silver Carp (Hypophthalmichthys molitrix) Can Mediate Gene Transposition in the Genome of Blunt Snout Bream (Megalobrama amblycephala).G3 (Bethesda, Md.) · 2015Article
- Alternative splicing acting as a bridge in evolution.Stem cell investigation · 2015Article
- Posttranslational modifications of proopiomelanocortin in vertebrates and their biological significance.Frontiers in endocrinology · 2013Review
- Analysis of the transcriptome of the Indonesian coelacanth Latimeria menadoensis.BMC genomics · 2013Article
- Analysis of phylogenetic signal in protostomial intron patterns using Mutual Information.Theory in biosciences = Theorie in den Biowissenschaften · 2013Article
- Multi-locus phylogenetic analysis reveals the pattern and tempo of bony fish evolution.PLoS currents · 2013Article
- A Phylogenomic Perspective on the Radiation of Ray-Finned Fishes Based upon Targeted Sequencing of Ultraconserved Elements (UCEs).PloS one · 2013Article
- The origin of modern frogs (Neobatrachia) was accompanied by acceleration in mitochondrial and nuclear substitution rates.BMC genomics · 2012Article
- Statistics and truth in phylogenomics.Molecular biology and evolution · 2012Review
- Article
- Integrating multi-origin expression data improves the resolution of deep phylogeny of ray-finned fish (Actinopterygii).Scientific reports · 2012Article
- Basal jawed vertebrate phylogenomics using transcriptomic data from Solexa sequencing.PloS one · 2012Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The evolutionary relationships of gnathostomes (jawed vertebrates), which comprise chondrichthyans (cartilaginous fishes), lobe-finned fishes (coelacanths and lungfishes), tetrapods, and actinopterygians (ray-finned fishes), have been debated for almost a century. Phylogenetic analyses based on fossils, morphology, and molecular sequences have generated different models of relationships that remain unresolved. We identified 13 derived shared molecular markers (synapomorphies) that define clades in the vertebrate lineage and used them to resolve the phylogenetic relationships of extant jawed vertebrates. Our markers include the presence or absence of insertions and deletions in coding sequences, nuclear introns, and alternatively spliced transcripts. The synapomorphies identified by us are congruent with each other and give rise to a single phylogenetic tree. This tree confirms that chondrichthyans are basal to all living gnathostomes, that lungfishes (Dipnoi) are the closest living relatives of tetrapods, and that bichirs (Cladistia) are the living members of the most ancient family of ray-finned fishes. Our study also provides molecular evidence to support the monophyly of living tetrapods and teleosts.
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