ArticleMolecular biology of the cell2001
Expression patterns of cell-type-specific genes in Dictyostelium.
Article in Molecular biology of the cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Lives in a gram of soil: linking life cycle biology to soil ecology.The ISME journal · 2026Review
- The Proteome ofProteomes · 2026Article
- Simulated Heat Waves Affect Cell Fate and Fitness in the Social Amoeba Dictyostelium discoideum.Microbial ecology · 2025Article
- Article
- Possible Involvement of the Nutrient and Energy Sensors mTORC1 and AMPK in Cell Fate Diversification in a Non-Metazoan Organism.Frontiers in cell and developmental biology · 2021Article
- Article
- Data on the expression and purification of Sestrin protein fromData in brief · 2019Article
- Extracellular signaling in Dictyostelium.The International journal of developmental biology · 2019Review
- Using the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosis.Journal of biomedical science · 2016Review
- Biological Activity of the Alternative Promoters of the Dictyostelium discoideum Adenylyl Cyclase A Gene.PloS one · 2016Article
- Article
- Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum.Disease models & mechanisms · 2015Article
- Systematic analysis of γ-aminobutyric acid (GABA) metabolism and function in the social amoeba Dictyostelium discoideum.The Journal of biological chemistry · 2013Article
- Conserved developmental transcriptomes in evolutionarily divergent species.Genome biology · 2010Article
- SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium.Developmental biology · 2008Article
- Prespore cell fate bias in G1 phase of the cell cycle in Dictyostelium discoideum.Eukaryotic cell · 2005Article
- Transcriptional switch of the dia1 and impA promoter during the growth/differentiation transition.Eukaryotic cell · 2005Article
- Peptide signaling during terminal differentiation of Dictyostelium.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Article
- CbfA, the C-module DNA-binding factor, plays an essential role in the initiation of Dictyostelium discoideum development.Eukaryotic cell · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Cell-type specific genes were recognized by interrogating microarrays carrying Dictyostelium gene fragments with probes prepared from fractions enriched in prestalk and prespore cells. Cell-type specific accumulation of mRNA from 17 newly identified genes was confirmed by Northern analyses. DNA microarrays carrying 690 targets were used to determine expression profiles during development. The profiles were fit to a biologically based kinetic equation to extract the times of transcription onset and cessation. Although the majority of the genes that were cell-type enriched at the slug stage were first expressed as the prespore and prestalk cells sorted out in aggregates, some were found to be expressed earlier before the cells had even aggregated. These early genes may have been initially expressed in all cells and then preferentially turned over in one or the other cell type. Alternatively, cell type divergence may start soon after the initiation of development.
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Registered trials
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