ArticleInfection and immunity2001
Mouse cytokine profiles associated with Brucella abortus RB51 vaccination or B. abortus 2308 infection.
Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- A Single Nasal Dose Vaccination with a Brucella abortus Mutant Potently Protects against Pulmonary Infection.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Evaluation of the immunogenicity and efficacy of a chimeric OMP25-OMP31 antigen in BALB/c mice.Veterinary medicine and science · 2021Article
- Nanoparticle or conventional adjuvants: which one improves immune response against Brucellosis?Iranian journal of basic medical sciences · 2019Article
- Immune Response of Calves Vaccinated with Brucella abortus S19 or RB51 and Revaccinated with RB51.PloS one · 2015Article
- What have we learned from brucellosis in the mouse model?Veterinary research · 2012Review
- Toll-like receptors are critical for clearance of Brucella and play different roles in development of adaptive immunity following aerosol challenge in mice.Frontiers in cellular and infection microbiology · 2012Article
- Human brucellosis is characterized by an intense Th1 profile associated with a defective monocyte function.Infection and immunity · 2010Article
- Establishment of systemic Brucella melitensis infection through the digestive tract requires urease, the type IV secretion system, and lipopolysaccharide O antigen.Infection and immunity · 2009Article
- Inactivation of the type IV secretion system reduces the Th1 polarization of the immune response to Brucella abortus infection.Infection and immunity · 2008Article
- Evaluation of protection afforded by Brucella abortus and Brucella melitensis unmarked deletion mutants exhibiting different rates of clearance in BALB/c mice.Infection and immunity · 2006Article
- Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used.Infection and immunity · 2003Article
- Brucella abortus RB51 induces protection in mice orally infected with the virulent strain B. abortus 2308.Infection and immunity · 2003Article
- Effect of exogenous interleukin-18 (IL-18) and IL-12 in the course of Brucella abortus 2308 infection in mice.Clinical and diagnostic laboratory immunology · 2002Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study indicated that mice immunized with Brucella abortus RB51 bacteria and subsequently challenged with B. abortus 2308 were protected from reinfection. After vaccination, both Th1 and Th2 cytokine patterns were observed. Of those, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based protection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.