ArticleThe Plant cell2001
Leaf-specific upregulation of chloroplast translocon genes by a CCT motif-containing protein, CIA 2.
Article in The Plant cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- CCT domain-containing genes in cereal crops: flowering time and beyond.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Pooled it
- Gene network analysis predicts the primary regulators of ABA-dependent transcriptional activation and repression in Populus roots.PLoS genetics · 2026Article
- Genome-wide analysis of the CCT gene family in Liriodendron chinense highlights potential functions in light signaling and chlorophyll biosynthesis.BMC plant biology · 2025Article
- A role for heritable transcriptomic variation in maize adaptation to temperate environments.Genome biology · 2023Article
- Arabidopsis CIA2 and CIL have distinct and overlapping functions in regulating chloroplast and flower development.Plant direct · 2022Article
- Article
- Mutation of theFrontiers in plant science · 2021Article
- The Arabidopsis AAC Proteins CIL and CIA2 Are Sub-functionalized Paralogs Involved in Chloroplast Development.Frontiers in plant science · 2021Article
- Sequence analysis and protein interactions of Arabidopsis CIA2 and CIL proteins.Botanical studies · 2020Article
- The White Stripes Featuring ALBOSTRIANS, a Chloroplast-Localized CCT Domain Protein.The Plant cell · 2019Article
- Leaf Variegation and Impaired Chloroplast Development Caused by a Truncated CCT Domain Gene inThe Plant cell · 2019Article
- Purine nucleotide biosynthetic gene GARS controls early chloroplast development in rice (Oryza sativa L.).Plant cell reports · 2019Article
- Article
- Article
- Chloroplast Iron Transport Proteins - Function and Impact on Plant Physiology.Frontiers in plant science · 2016Review
- gigantea suppresses immutans variegation by interactions with cytokinin and gibberellin signaling pathways.Plant physiology · 2014Article
- Border control: selectivity of chloroplast protein import and regulation at the TOC-complex.Frontiers in plant science · 2014Review
- CIA2 coordinately up-regulates protein import and synthesis in leaf chloroplasts.Plant physiology · 2009Article
- GLK transcription factors coordinate expression of the photosynthetic apparatus in Arabidopsis.The Plant cell · 2009Article
- Arabidopsis stromal 70-kD heat shock proteins are essential for plant development and important for thermotolerance of germinating seeds.Plant physiology · 2008Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chloroplasts are a major destination of protein traffic within leaf cells. Protein import into chloroplasts is mediated by a set of translocon complexes at the chloroplast envelope. Current data indicate that the expression of translocon genes is regulated in a tissue-specific manner, possibly to accommodate the higher import demand of chloroplasts in leaves and the lower demand of plastids in other tissues. We have designed a transgene-based positive screen to isolate mutants disrupted in protein import into plastids. The first locus we isolated, CIA2, encodes a protein containing a motif conserved within the CCT family of transcription factors. Biochemical analysis indicates that CIA2 is responsible for specific upregulation of the translocon genes atToc33 and atToc75 in leaves. Identification of CIA2 provides new insights into the tissue-specific regulation of translocon gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.