ReviewJournal of mammary gland biology and neoplasia2001
Milk lipid globules and their surrounding membrane: a brief history and perspectives for future research.
Review in Journal of mammary gland biology and neoplasia, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- AMP-activated protein kinase mediates (-)-epigallocatechin-3-gallate (EGCG) to promote lipid synthesis in mastitis cows.Animal biotechnology · 2024Article
- Bactrian Camel Milk: Chemical Composition, Bioactivities, Processing Techniques, and Economic Potential in China.Molecules (Basel, Switzerland) · 2024Review
- The Effects ofACS omega · 2024Article
- Utilization of low-temperature heating method to improve skim milk production: Microstructure, stability, and constituents of milk fat globule membrane.Food chemistry: X · 2024Article
- Brain-immune-gut benefits with early life supplementation of milk fat globule membrane.JGH open : an open access journal of gastroenterology and hepatology · 2022Review
- Colostrogenesis: Role and Mechanism of the Bovine Fc Receptor of the Neonate (FcRn).Journal of mammary gland biology and neoplasia · 2021Review
- Exploration of Proteomics Analysis of Crop Milk in Pigeons (ACS omega · 2021Article
- A Comprehensive Review of the Composition, Nutritional Value, and Functional Properties of Camel Milk Fat.Foods (Basel, Switzerland) · 2021Review
- Increased gene dosage for β- and κ-casein in transgenic cattle improves milk composition through complex effects.Scientific reports · 2016Article
- Cholesterol transport and regulation in the mammary gland.Journal of mammary gland biology and neoplasia · 2014Review
- Comparative proteomics of milk fat globule membrane proteins from transgenic cloned cattle.PloS one · 2014Article
- Integration of maternal genome into the neonate genome through breast milk mRNA transcripts and reverse transcriptase.Theoretical biology & medical modelling · 2012Review
- Maintaining RNA integrity in a homogeneous population of mammary epithelial cells isolated by Laser Capture Microdissection.BMC cell biology · 2010Article
- Composition and fatty acid distribution of bovine milk phospholipids from processed milk products.Journal of agricultural and food chemistry · 2010Article
- Using confocal laser scanning microscopy to probe the milk fat globule membrane and associated proteins.Journal of agricultural and food chemistry · 2010Article
- Is increased fat content of hindmilk due to the size or the number of milk fat globules?International breastfeeding journal · 2009Article
- Butyrophilin controls milk fat globule secretion.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland.Genes & development · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most of the lipids in milk are triacylglycerols that occur in globules surrounded by a membrane derived from cellular membranes. This membrane, the milk-fat or milk-lipid globule membrane (MLGM), surrounds globules during the process of their secretion from the cell. The nature and cellular origin of the milk lipid globule membrane has been the subject of a considerable amount of research. Milk lipid globules originate as very small lipid droplets formed on or in the endoplasmic reticulum followed by release into the cytosol. These droplets consist of a triacylglycerol-rich core coated with a layer of proteins and polar lipids. How these droplets are formed, how they can grow in volume, how they move through the cell, and how they are secreted are questions that have been the basis for a number of investigations. While the general outlines of droplet formation, growth, movement, and secretion are known, virtually no molecular details of any of these processes have been elucidated. In this article I have presented a brief historical account of research on milk fat globules, their surrounding membrane, and on aspects of the intracellular origin, growth, and secretion of milk lipid globules. I have also attempted to call attention to those areas where further research is needed to gain a better understanding of the processes involved.
Indexed as
Identifiers
11547904What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.