ArticleJournal of molecular evolution1995
The origin of life--did it occur at high temperatures?
Article in Journal of molecular evolution, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
42 citing papers in PubMed.
- Computational Prediction of One-Electron Oxidation Potentials for Cytosine and Uracil Epigenetic Derivatives.The journal of physical chemistry. A · 2025Article
- The Last Universal Common Ancestor of Ribosome-Encoding Organisms: Portrait of LUCA.Journal of molecular evolution · 2024Review
- New Insights on the Origin of Life: The Role of Silico-Carbonates of Ba (II) to Preserve DNA against Highly Intense UV Radiation.ACS omega · 2023Article
- Setting the geological scene for the origin of life and continuing open questions about its emergence.Frontiers in astronomy and space sciences · 2023Article
- Dissipative Photochemical Abiogenesis of the Purines.Entropy (Basel, Switzerland) · 2022Article
- Silica-Carbonate of Ba(II) and FeACS omega · 2021Article
- Plausible Emergence and Self Assembly of a Primitive Phospholipid from Reduced Phosphorus on the Primordial Earth.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2021Review
- Plausibility of Early Life in a Relatively Wide Temperature Range: Clues from Simulated Metabolic Network Expansion.Life (Basel, Switzerland) · 2021Article
- Questioning the radiation limits of life: Ignicoccus hospitalis between replication and VBNC.Archives of microbiology · 2021Article
- Influence of Abiotic Factors in the Chemical Origin of Life: Biomorphs as a Study Model.ACS omega · 2021Review
- The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine.Entropy (Basel, Switzerland) · 2021Article
- The Role of Meteorite Impacts in the Origin of Life.Astrobiology · 2020Article
- The Prebiotic Provenance of Semi-Aqueous Solvents.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2020Article
- Primitive Photosynthetic Architectures Based on Self-Organization and Chemical Evolution of Amino Acids and Metal Ions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- Prebiotic Synthesis of Glycine from Ethanolamine in Simulated Archean Alkaline Hydrothermal Vents.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Article
- Cataclysm No More: New Views on the Timing and Delivery of Lunar Impactors.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Review
- Characterization of Reconstructed Ancestral Proteins Suggests a Change in Temperature of the Ancient Biosphere.Life (Basel, Switzerland) · 2017Review
- Habitability on Early Mars and the Search for Biosignatures with the ExoMars Rover.Astrobiology · 2017Article
- Cryosphere and Psychrophiles: Insights into a Cold Origin of Life?Life (Basel, Switzerland) · 2017Review
- The Astrobiology Primer v2.0.Astrobiology · 2016Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A high-temperature origin of life has been proposed, largely for the reason that the hyperthermophiles are claimed to be the last common ancestor of modern organisms. Even if they are the oldest extant organisms, which is in dispute, their existence can say nothing about the temperatures of the origin of life, the RNA world, and organisms preceding the hyperthermophiles. There is no geological evidence for the physical setting of the origin of life because there are no unmetamorphosed rocks from that period. Prebiotic chemistry points to a low-temperature origin because most biochemicals decompose rather rapidly at temperatures of 100 degrees C (e.g., half-lives are 73 min for ribose, 21 days for cytosine, and 204 days for adenine). Hyperthermophiles may appear at the base of some phylogenetic trees because they outcompeted the mesophiles when they adapted to lower temperatures, possibly due to enhanced production of heat-shock proteins.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.