Evidence map›Paper›PMID 11537409›Full record

ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1990

Oligomerization reactions of deoxyribonucleotides on montmorillonite clay: the effect of mononucleotide structure, phosphate activation and montmorillonite composition on phosphodiester bond formation.

J P Ferris, Kamaluddin, G Ertem

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Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Adsorption of ribose nucleotides on manganese oxides with varied mn/o ratio: implications for chemical evolution.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2011
    Article
  3. Article
  4. Article
  5. Catalysis and prebiotic RNA synthesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1993
    Article
  6. Some biochemical properties of an acyclic oligonucleotide analogue. A plausible ancestor of the DNA?Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1993
    Article
  7. Oligomerization reactions of ribonucleotides: the reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1992
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J P FerrisRensselaer Polytechnic Institute, Troy, NY 12180-3590, USA.
Kamaluddin
G Ertem
Rensselaer Polytechnic Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2'-d-5'-GMP and 2'-d-5'-AMP bind 2 times more strongly to montmorillonite 22A than do 2'-d-5'-CMP and 5'-TMP. The dinucleotide d(pG)2 forms in 9.2% yield and the cyclic dinucleotide c(dpG)2 in 5.4% yield in the reaction of 2'-d-5'-GMP with EDAC in the presence of montmorillonite 22A. The yield of d(pC)2 (2.0%) is significantly lower but comparable to that obtained from 5'-TMP. The yield of dimers which contain the phosphodiester bond decreases as the reaction medium is changed from 0.2 M NaCl to a mixture of 0.2 M NaCl and 0.075 M MgCl2. A low yield of d(pA)2 was observed in the condensation reaction of 5'-ImdpA on montmorillonite 22A. The cyclic nucleotide (3',5'-cdAMP) was obtained in 14% yield from 3'-ImdpA. The yield of d(pA)2 obtained when EDAC is used as the condensing agent increases with increasing iron content of the Na(+)-montmorillonite used as a catalyst. Evidence is presented which shows that the acidity of the Na(+)-montmorillonite is a necessary but not sufficient factor for the montmorillonite catalysis of phosphodiester bond formation.

Indexed as

Origin of LifeBentoniteBinding SitesCarbodiimidesCatalysisCytidine MonophosphateDeoxyadenine NucleotidesDeoxyribonucleotidesEvolution, MolecularGuanosine MonophosphateImidazolesIronMagnesium ChlorideOrganophosphatesSodium ChlorideTemplates, Genetic1-ethyl-3-(3-dimethylaminoethyl)carbodiimide2'-deoxy-5'-adenosine monophosphateBentoniteCarbodiimidesCytidine MonophosphateDeoxyadenine NucleotidesDeoxyribonucleotidesGuanosine MonophosphateImidazolesIronMagnesium ChlorideOrganophosphatesSodium ChlorideNASA Discipline ExobiologyNon-NASA Center

Identifiers

PMID11537409
OpenAlexW2063316712

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.