Evidence map›Paper›PMID 11536772›Full record

ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1996

Oligomerization of negatively-charged amino acids by carbonyldiimidazole.

A R Hill, L E Orgel

Abstract read
PubMed Publisher
In one paragraph

Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Potassium ions are more effective than sodium ions in salt induced peptide formation.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013
    Article
  3. Sodium chloride enhanced oligomerization of L-glutamic acid in aqueous solution.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A R HillThe Salk Institute for Biological Studies, San Diego, California 92186-5800, USA.
L E Orgel
Salk Institute for Biological Studies · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The carbonyldiimidazole-induced oligomerizations of aspartic acid, glutamic acid and O-phospho-serine are amongst the most efficient reported syntheses of biopolymers in aqueous solution. The dependence of the yields of products on the concentrations of reagents, the temperature and the enantiomeric composition of the substrate amino acids are reported. Catalysis by metal ions, particularly by Mg2+, is described. These reactions do not generate significant amounts of material in the size-range of several tens of residues that are thought to be needed for a polymer to function as a genetic material.

Indexed as

Evolution, ChemicalAspartic AcidCatalysisGlutamic AcidImidazolesMagnesiumPhosphoserinePolymersTemperatureAspartic AcidGlutamic AcidImidazolesMagnesiumN,N-carbonyldiimidazolePhosphoserinePolymersNASA Discipline ExobiologyNon-NASA Center

Identifiers

PMID11536772
OpenAlexW2063498140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.