Evidence map›Paper›PMID 11536743›Full record

ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1996

Catalysis of the oligomerization of O-phospho-serine, aspartic acid, or glutamic acid by cationic micelles.

C Bohler, A R Hill, L E Orgel

Abstract read
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In one paragraph

Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. A hypothesis about the origin of biology.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2015
    Article
  3. Amino acid interaction with and adsorption on clays: FT-IR and Mössbauer spectroscopy and X-ray diffractometry investigations.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2007
    Article
  4. The first living systems: a bioenergetic perspective.Microbiology and molecular biology reviews : MMBR · 1997
    Review
  5. Oligomerization of negatively-charged amino acids by carbonyldiimidazole.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1996
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

C BohlerThe Salk Institute for Biological Studies, San Diego, CA 92186-5800, USA.
A R Hill
L E Orgel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of relatively concentrated aqueous solutions of O-phospho-serine (50 mM), aspartic acid (100 mM) or glutamic acid (100 mM) with carbonyldiimidazole leads to the formation of an activated intermediate that oligomerizes efficiently. When the concentration of amino acid is reduced tenfold, few long oligomers can be detected. Positively-charged cetyltrimethyl ammonium bromide micelles concentrate the negatively-charged activated intermediates of the amino acids at their surfaces and catalyze efficient oligomerization even from dilute solutions.

Indexed as

MicellesAmino AcidsAspartic AcidCatalysisCetrimoniumCetrimonium CompoundsEvolution, MolecularGlutamic AcidHydrogen-Ion ConcentrationImidazolesOligopeptidesPhosphoserineAmino AcidsAspartic AcidCetrimoniumCetrimonium CompoundsGlutamic AcidImidazolesMicellesN,N-carbonyldiimidazoleOligopeptidesPhosphoserineNASA Discipline ExobiologyNon-NASA Center

Identifiers

PMID11536743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.