ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1995
Binding of adenine and adenine-related compounds to the clay montmorillonite and the mineral hydroxylapatite.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 61 citations in OpenAlex.
- Article
- Review
- Clays and the Origin of Life: The Experiments.Life (Basel, Switzerland) · 2022Review
- How do Nucleotides Adsorb Onto Clays?Life (Basel, Switzerland) · 2018Article
- Salinity Effects on the Adsorption of Nucleic Acid Compounds on Na-Montmorillonite: a Prebiotic Chemistry Experiment.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2018Article
- Factors affecting the association of single- and double-stranded RNAs with montmorillonite nanoclays.International journal of biological macromolecules · 2018Article
- A Prebiotic Chemistry Experiment on the Adsorption of Nucleic Acids Bases onto a Natural Zeolite.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2015Article
- Adsorption of nucleic Acid bases, ribose, and phosphate by some clay minerals.Life (Basel, Switzerland) · 2015Review
- Adsorption of adenine and thymine on zeolites: FT-IR and EPR spectroscopy and X-ray diffractometry and SEM studies.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2012Article
- Adsorption of adenine, cytosine, thymine, and uracil on sulfide-modified montmorillonite: FT-IR, Mössbauer and EPR spectroscopy and X-ray diffractometry studies.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2011Article
- Nucleic acids bind to nanoparticulate iron (II) monosulphide in aqueous solutions.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2008Article
- Differential adsorption of nucleic acid bases: Relevance to the origin of life.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Biochemical evolution. I. Polymerization On internal, organophilic silica surfaces of dealuminated zeolites and feldspars.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
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2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The first living things may have consisted of no more than RNA or RNA-like molecules bound to the surfaces of mineral particles. A key aspect of this theory is that these mineral particles have binding sites for RNA and its prebiotic precursors. The object of this study is to explore the binding properties of two of the best studied minerals, montmorillonite and hydroxylapatite, for possible precursors of RNA. The list of compounds investigated includes purines, pyrimidines, nucleosides, nucleotides, nucleotide coenzymes, diaminomaleonitrile and aminoimidazole carboxamide. Affinities for hydroxylapatite are dominated by ionic interactions between negatively charged small molecules and positively charged sites in the mineral. Binding to montmorillonite presents a more complex picture. These clay particles have a high affinity for organic ring structures which is augmented if they are positively charged. This binding probably takes place on the negatively charged faces of these sheet-like clay particles. Additional binding sites on the edges of these sheets have a moderate affinity for negatively charged molecules. Small molecules that bind to these minerals sometimes bind independently to sites on the minerals and sometimes bind cooperatively with favorable interactions between the bound molecules.
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