ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1992
Oligomerization reactions of ribonucleotides: the reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 55 citations in OpenAlex.
- The role of minerals in prebiotic evolution: Implications for identifying worlds with the potential for life's origin.Fundamental research · 2026Review
- Clay Minerals, Panacea or Parameter in RNA Oligomerization?Journal of molecular evolution · 2026Article
- Visualizing RNA polymers produced by hot wet-dry cycling.Scientific reports · 2022Article
- Nanoscale Anatomy of Iron-Silica Self-Organized Membranes: Implications for Prebiotic Chemistry.Angewandte Chemie (International ed. in English) · 2021Article
- Regioselective formation of RNA strands in the absence of magnesium ions.Nucleic acids research · 2020Article
- Mineral Surface Chemistry and Nanoparticle-aggregation Control Membrane Self-Assembly.Scientific reports · 2017Article
- Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research.Beilstein journal of organic chemistry · 2017Article
- Synergism and mutualism in non-enzymatic RNA polymerization.Life (Basel, Switzerland) · 2014Review
- Correlation between the extent of catalytic activity and charge density of montmorillonites.Astrobiology · 2010Article
- Kinetic analysis of oligo(C) formation from the 5'-monophosphorimidazolide of cytidine with Pb(II) ion catalyst at 10-75 degrees C.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2007Article
- Montmorillonite-catalysed formation of RNA oligomers: the possible role of catalysis in the origins of life.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Article
- The effect of smectite composition on the catalysis of peptide bond formation.Journal of molecular evolution · 1996Article
- Oligomerization of uridine phosphorimidazolides on montmorillonite: a model for the prebiotic synthesis of RNA on minerals.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1996Article
- The search for missing links between self-replicating nucleic acids and the RNA world.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1995Review
- Adsorption of small biological molecules on silica from diluted aqueous solutions: quantitative characterization and implications to the Bernal's hypothesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1995Article
- Catalysis and prebiotic RNA synthesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1993Article
- Applicability of PM3 to transphosphorylation reaction path: toward designing a minimal ribozyme.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 1993Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reaction of ImpA in the presence of Na+ -montmorillonite 22A or Na+ -Volclay in aqueous, pH 8 solution gives a 50-60% yield of dimers and trimers (pA)2 and (pA)3. The ratio of 3',5'-phosphodiester bond formation is twice as great as 2',5'-bond formation. The reaction requires the presence of Mg2+ and is inhibited by 0.4 M imidazole. N-methylimidazole enhances the rate of the reaction but does not cause major changes in yield or product composition. Higher yields were obtained when Li+ -or Ca2+ -montmorillonites were used in place of Na+ -montmorillonite. Little or no phosphodiester bond formation was observed with Mg2+ - or Al3+ -montmorillonite. Montmorillonites other than 22A and Volclay exhibited little or no catalysis. In addition, little or no catalysis was exhibited in ferrugenous smectite, nontronite, allophane, imogolite or sepiolite. Oligomers were also formed by the reaction of ImpG, 2-methylImpG, ImpC and ImpU in the presence of Na+ -montmorillonite. The pyrimidine nucleotides gave significantly lower yields of oligomers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.