ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life1992
Condensation of vaporous amino acids in the presence of silica. Formation of bi- and tricyclic amidines.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 15 citations in OpenAlex.
- Glycine Polymerization on Oxide Minerals.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Article
- Biochemical evolution. I. Polymerization On internal, organophilic silica surfaces of dealuminated zeolites and feldspars.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
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1 author at 1 institution in 1 country.
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Abstract
Amino acids (alanine, valine, norvaline, leucine, and 2-aminoisobutyric acid) were subjected to repeated (5-9 times) sublimation in the presence of silica at temperature of 220-240 degrees C. The major amino acid condensation products were diketopiperazines (DKPs) in yields of 27-89%. Mixtures of by-products have been isolated from the DKPs by means of chloroform extraction. On the basis of fast atom bombardment mass spectrometric studies of the mixtures it is proposed that under these conditions further dehydration proceeds resulting in bicyclic (BCA) and tricyclic (TCA) amidine derivatives of DKPs; the BCA formation has been confirmed by means of IR and 1H NMR spectroscopy in the case of 2-aminoisobutyric acid. During the sublimation, thermal destruction of the cyclic products was also observed accompanied by the cycle degradation and cleavage of alkyl substituents. The BCAs and TCAs are considered as possible sources of linear di- and tripeptides.
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