ArticleHuman reproduction (Oxford, England)2001
Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome.
Article in Human reproduction (Oxford, England), 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of the Combination Liraglutide and Metformin on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With Polycystic Ovarian Syndrome, Obesity and Infertility
Pilot Study on the Effects of Fasting Mimicking Diet (FMD) in Women With Polycystic
Who cites it
70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 346 citations in OpenAlex.
- Association between VEGF gene polymorphisms (11 sites) and polycystic ovary syndrome risk.Bioscience reports · 2020Pooled it
- Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis.Systematic reviews · 2019Pooled it
- Pooled it
- Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline.The Journal of clinical endocrinology and metabolism · 2013 · on this mapGuideline
- Effect of combined metformin and oral contraceptive therapy on metabolic factors and endothelial function in overweight and obese women with polycystic ovary syndrome.Fertility and sterility · 2011Trial
- Assessment of insulin resistance and impaired glucose tolerance in lean women with polycystic ovary syndrome.Journal of women's health (2002) · 2011Trial
- Urinary Albumin-to-Creatinine Ratio Across Phenotypes of Polycystic Ovary Syndrome: A Phenotype-Based Evaluation.Metabolites · 2026Article
- Extended Oral Glucose Tolerance Test Unmasks Intermediate Metabolic Phenotypes in Polycystic Ovary Syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- The Effects of Different Exercises on Insulin Resistance and Testosterone Changes in Women with Polycystic Ovarian Syndrome: A Network Meta-Analysis Study.Healthcare (Basel, Switzerland) · 2025Review
- The frequency of polycystic ovary syndrome in women with prediabetes compared with normoglycemic women.Frontiers in endocrinology · 2025Article
- The latest reports and treatment methods on polycystic ovary syndrome.Annals of medicine · 2024Review
- Gut Microbes in Polycystic Ovary Syndrome and Associated Comorbidities; Type 2 Diabetes, Non-Alcoholic Fatty Liver Disease (NAFLD), Cardiovascular Disease (CVD), and the Potential of Microbial Therapeutics.Probiotics and antimicrobial proteins · 2024Review
- SHBG Levels Do Not Correlate with Insulin Levels in PCOS with Appropriate Fasting Insulin Sensitivity.Journal of clinical medicine · 2024Article
- Transcriptomic analysis identifies diagnostic genes in polycystic ovary syndrome and periodontitis.European journal of medical research · 2024Article
- Roles of estrogen and its receptors in polycystic ovary syndrome.Frontiers in cell and developmental biology · 2024Review
- Influence of Phenotypes on the Metabolic Syndrome of Women with Polycystic Ovary Syndrome over a Six-Year Follow-Up in Brazil.Biomedicines · 2023Article
- The role of polycystic ovary syndrome in preclinical left ventricular diastolic dysfunction: an echocardiographic approach: a systematic review and meta-analysis.Cardiovascular endocrinology & metabolism · 2023Review
- Assessment of Type 2 Diabetes Risk in Young Women with Polycystic Ovary Syndrome.Diagnostics (Basel, Switzerland) · 2023Review
- Review
- Polycystic ovary syndrome and type 2 diabetes mellitus: A state-of-the-art review.World journal of diabetes · 2022Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCross-sectional studies have shown a high frequency of impaired glucose tolerance (IGT) and non-insulin dependent diabetes mellitus (NIDDM) in women with polycystic ovarian syndrome (PCOS). However, little is known about the change in glucose tolerance that occurs over a period of several years in women with PCOS.
methodsSixty-seven women with PCOS received a 75 g glucose tolerance test and measurement of lipids at baseline and at follow-up after an average time of 6.2 years. All women followed prospectively had normal glucose tolerance (n = 54) or IGT (n = 13) at the start of the study.
resultsChange in glycaemic control from baseline was frequent, with 5/54 (9%) of normoglycaemic women at baseline developing IGT and a further 4/54 (8%) moving directly from normoglycaemic to NIDDM. For women with IGT at baseline, 7/13 (54%) had NIDDM at follow-up. Body mass index (BMI) at baseline was an independent significant predictor of adverse change in glycaemic control.
conclusionsWomen with PCOS, particularly those with a high BMI, should be reviewed regularly with respect to IGT or NIDDM, as the frequency of impaired glycaemic control is high, and that the rate of conversion from normal glucose tolerance to IGT or NIDDM, or from IGT to NIDDM is substantial.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.