ArticleProceedings of the National Academy of Sciences of the United States of America2001
An essential role of a TatC homologue of a Delta pH- dependent protein transporter in thylakoid membrane formation during chloroplast development in Arabidopsis thaliana.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 99 citations in OpenAlex.
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- OsFeSOD3 Functions as an Enzymatic Component of the PEP Complex, Bifunctionally Regulating Chloroplastic ROS Metabolism and Chloroplast Biogenesis in Rice.Plant biotechnology journal · 2026Article
- Yellow barley xan-m mutants are deficient in the motor unit SECA1 of the SEC1 translocase system.Planta · 2025Article
- PEP-ASSOCIATED PROTEIN 3 regulates rice tiller formation and grain yield by controlling chloroplast biogenesis.Plant physiology · 2024Article
- Strategies of chemolithoautotrophs adapting to high temperature and extremely acidic conditions in a shallow hydrothermal ecosystem.Microbiome · 2023Article
- Plastid-Localized EMB2726 Is Involved in Chloroplast Biogenesis and Early Embryo Development inFrontiers in plant science · 2021Article
- Osj10gBTF3-Mediated Import of Chloroplast Protein Is Essential for Pollen Development in Rice.Frontiers in plant science · 2021Article
- An isoform of the plastid RNA polymerase-associated protein FSD3 negatively regulates chloroplast development.BMC plant biology · 2019Article
- Functional analyses of lipocalin proteins in tomato.Plant biotechnology (Tokyo, Japan) · 2018Article
- A nuclear-encoded protein, mTERF6, mediates transcription termination of rpoA polycistron for plastid-encoded RNA polymerase-dependent chloroplast gene expression and chloroplast development.Scientific reports · 2018Article
- Suppressors of the Chloroplast Protein Import MutantThe Plant cell · 2017Article
- pTAC10, a Key Subunit of Plastid-Encoded RNA Polymerase, Promotes Chloroplast Development.Plant physiology · 2017Article
- Two Chloroplast Proteins Suppress Drought Resistance by Affecting ROS Production in Guard Cells.Plant physiology · 2016Article
- Integrated analysis of transcriptome and metabolome of Arabidopsis albino or pale green mutants with disrupted nuclear-encoded chloroplast proteins.Plant molecular biology · 2014Article
- Mapping the signal peptide binding and oligomer contact sites of the core subunit of the pea twin arginine protein translocase.The Plant cell · 2013Article
- Intra-plastid protein trafficking: how plant cells adapted prokaryotic mechanisms to the eukaryotic condition.Biochimica et biophysica acta · 2013Review
- The reduced plastid-encoded polymerase-dependent plastid gene expression leads to the delayed greening of the Arabidopsis fln2 mutant.PloS one · 2013Article
- Common and specific protein accumulation patterns in different albino/pale-green mutants reveals regulon organization at the proteome level.Plant physiology · 2012Article
- The GDC1 gene encodes a novel ankyrin domain-containing protein that is essential for grana formation in Arabidopsis.Plant physiology · 2011Article
- Plastids contain a second sec translocase system with essential functions.Plant physiology · 2011Article
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7 authors at 1 institution in 1 country.
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Abstract
At least three transport systems function in targeting nuclear-encoded chloroplast proteins to the chloroplast thylakoid membrane. One of these systems requires a thylakoid pH gradient and is named the DeltapH-dependent protein transport system. A similar DeltapH export system of Escherichia coli contains four components, twin arginine translocation A (TatA), TatB, TatC, and TatE. TatC is a major component of the DeltapH-dependent protein transporter in E. coli and functions in the translocation of tightly folded proteins across membranes. We have isolated four transposon-inserted albino mutants named albino and pale green 2 (apg2) from Arabidopsis thaliana and showed that the transposons were inserted into different sites of a single gene. The APG2 gene product (named cpTatC) has sequence similarity with bacterial TatC and contains six putative transmembrane domains, including bacterial TatC proteins and a transit peptide in its N terminus. apg2 mutants showed albino phenotypes and could not grow in soil. The apg2 plastids were highly vacuolated, lacked internal membrane structures and lamellae of the thylakoid membrane, and contained many densely stained globule structures, like undifferentiated proplastids. Immunoblot analysis detected no thylakoid membrane proteins such as D1, light-harvesting complex, and OE23 in apg2 plastids, whereas soluble proteins such as rubisco large and small subunits were not decreased. These results indicate an essential role of cpTatC in chloroplast development, especially in thylakoid membrane formation.
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