Evidence map›Paper›PMID 11526190›Full record

ArticleJournal of clinical microbiology2001

Molecular typing of the etiologic agent of human granulocytic ehrlichiosis.

S E Carter, M D Ravyn, Y Xu, R C Johnson

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Agents of human anaplasmosis and Lyme disease at Camp Ripley, Minnesota.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2011
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S E CarterDepartment of Microbiology, University of Minnesota Academic Health Center, Minneapolis, Minnesota 55455, USA.
M D Ravyn
Y Xu
R C Johnson

Funding

HUMAN GRANULOCYTIC EHRLICHIOSIS: NORTH CENTRAL U.S.R01AI047896 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JOHNSON, RUSSELL C · 2001 to 2005
$1.8M
NIAID NIH HHS AI47896PHS HHS I40952
6 · The paper itself

Abstract

The p44 gene of the agent of human granulocytic ehrlichiosis (aoHGE) encodes a 44-kDa major outer surface protein. A technique was developed for the typing of the aoHGE based on the PCR amplification of the p44 gene followed by a multiple restriction digest with HindIII, EcoRV, and AspI to generate restriction fragment length polymorphism patterns. Twenty-four samples of the aoHGE were collected from geographically dispersed sites in the United States and included isolates from humans, equines, canines, small mammals, and ticks. Six granulocytic ehrlichiosis (GE) types were identified. The GE typing method is relatively simple to perform, is reproducible, and is able to differentiate among the various isolates of granulocytic ehrlichiae in the United States. These characteristics suggest that this GE typing method may be an important epizootiological and epidemiological tool.

Indexed as

Polymerase Chain ReactionPolymorphism, Restriction Fragment LengthAnimalsBacterial Outer Membrane ProteinsBacterial Typing TechniquesDogsEhrlichiaEhrlichiosisHumansBacterial Outer Membrane Proteins

Identifiers

PMID11526190
PMCPMC88358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.