Evidence map›Paper›PMID 11526174›Full record

ArticleJournal of clinical microbiology2001

Sequence typing confirms that Campylobacter jejuni strains associated with Guillain-Barré and Miller-Fisher syndromes are of diverse genetic lineage, serotype, and flagella type.

K E Dingle, N Van Den Braak, F M Colles, L J Price, D L Woodward, F G Rodgers, H P Endtz, A Van Belkum, M C Maiden

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 90 citations in OpenAlex.

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  4. Treatment with the Probiotic Product AviguardInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

K E DingleWellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, United Kingdom.
N Van Den Braak
F M Colles
L J Price
D L Woodward
F G Rodgers
H P Endtz
A Van Belkum
M C Maiden
Erasmus MC · NLUniversity of Oxford · GBCentre for Human Genetics · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Guillain-Barré syndrome (GBS) and Miller-Fisher syndrome (MFS) are correlated with prior infection by Campylobacter jejuni in up to 40% of cases. Nucleotide sequence-based typing of 25 C. jejuni isolates associated with neuropathy permitted robust comparisons with equivalent data from approximately 800 C. jejuni isolates not associated with neuropathy. A total of 13 genetic lineages and 20 flaA short variable region nucleotide sequences were present among the 25 isolates. A minority of isolates (4 of 25) had the flaA short variable region nucleotide sequences that were previously proposed as a marker for GBS-associated isolates. These 4 isolates probably represented the Penner serotype 19 lineage, which has been proposed to have an association with GBS.

Indexed as

Sequence Analysis, DNABacterial Typing TechniquesBase SequenceCampylobacter InfectionsCampylobacter jejuniDNA, BacterialFlagellaFlagellinGenetic VariationGuillain-Barre SyndromeHumansMiller Fisher SyndromeMolecular Sequence DataSerotypingDNA, BacterialflaA protein, bacteriaFlagellin

Identifiers

PMID11526174
PMCPMC88342
OpenAlexW2152158227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.