ArticleProceedings of the National Academy of Sciences of the United States of America2001
Accelerated regulatory gene evolution in an adaptive radiation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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51 citing papers in PubMed.
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- Evolutionary Dynamics and Expression Divergence of thePlants (Basel, Switzerland) · 2025Article
- Paleopteran molecular clock: Time drift and recent acceleration.Ecology and evolution · 2024Article
- The genetic regulatory architecture and epigenomic basis for age-related changes in rattlesnake venom.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Evaluating the Accuracy of Methods for Detecting Correlated Rates of Molecular and Morphological Evolution.Systematic biology · 2023Article
- The Population Genomics of Increased Virulence and Antibiotic Resistance in Human Commensal Escherichia coli over 30 Years in France.Applied and environmental microbiology · 2022Article
- A Genome for Bidens hawaiensis: A Member of a Hexaploid Hawaiian Plant Adaptive Radiation.The Journal of heredity · 2022Article
- Co-expression network analyses of anthocyanin biosynthesis genes in Ruellia (Wild Petunias; Acanthaceae).BMC ecology and evolution · 2022Article
- Ancestral polymorphisms shape the adaptive radiation ofProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Extensive alternative splicing triggered by mitonuclear mismatch in naturally introgressed Rhinolophus bats.Ecology and evolution · 2021Article
- Reconstruction of the spatio-temporal diversification and ecological niche evolution of Helianthemum (Cistaceae) in the Canary Islands using genotyping-by-sequencing data.Annals of botany · 2021Article
- Deep time diversity and the early radiations of birds.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Gene expression dynamics during rapid organismal diversification in African cichlid fishes.Nature ecology & evolution · 2021Article
- The Developmental Gene Hypothesis for Punctuated Equilibrium: Combined Roles of Developmental Regulatory Genes and Transposable Elements.BioEssays : news and reviews in molecular, cellular and developmental biology · 2020Review
- Hybridization increases population variation during adaptive radiation.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Accelerated evolution at chaperone promoters among Antarctic notothenioid fishes.BMC evolutionary biology · 2019Article
- Island woodiness underpins accelerated disparification in plant radiations.The New phytologist · 2019Article
- Dosage imbalance of B- and C-class genes causes petaloid-stamen relating to FBMC plant biology · 2018Article
- Evolutionary divergence of 3' UTRs in cichlid fishes.BMC genomics · 2018Article
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3 authors.
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Abstract
The disparity between rates of morphological and molecular evolution remains a key paradox in evolutionary genetics. A proposed resolution to this paradox has been the conjecture that morphological evolution proceeds via diversification in regulatory loci, and that phenotypic evolution may correlate better with regulatory gene divergence. This conjecture can be tested by examining rates of regulatory gene evolution in species that display rapid morphological diversification within adaptive radiations. We have isolated homologues to the Arabidopsis APETALA3 (ASAP3/TM6) and APETALA1 (ASAP1) floral regulatory genes and the CHLOROPHYLL A/B BINDING PROTEIN9 (ASCAB9) photosynthetic structural gene from species in the Hawaiian silversword alliance, a premier example of plant adaptive radiation. We have compared rates of regulatory and structural gene evolution in the Hawaiian species to those in related species of North American tarweeds. Molecular evolutionary analyses indicate significant increases in nonsynonymous relative to synonymous nucleotide substitution rates in the ASAP3/TM6 and ASAP1 regulatory genes in the rapidly evolving Hawaiian species. By contrast, no general increase is evident in neutral mutation rates for these loci in the Hawaiian species. An increase in nonsynonymous relative to synonymous nucleotide substitution rate is also evident in the ASCAB9 structural gene in the Hawaiian species, but not to the extent displayed in the regulatory loci. The significantly accelerated rates of regulatory gene evolution in the Hawaiian species may reflect the influence of allopolyploidy or of selection and adaptive divergence. The analyses suggest that accelerated rates of regulatory gene evolution may accompany rapid morphological diversification in adaptive radiations.
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