ReviewGenome biology2001
Histone variants: are they functionally heterogeneous?
Review in Genome biology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed.
- Mass spectrometry-intensive top-down proteomics: an update on technology advancements and biomedical applications.Analytical methods : advancing methods and applications · 2024Review
- Article
- Effects of H2A.B incorporation on nucleosome structures and dynamics.Biophysical journal · 2021Article
- Review
- Replication-dependent histone isoforms: a new source of complexity in chromatin structure and function.Nucleic acids research · 2018Review
- Independent Biological and Biochemical Functions for Individual Structural Domains of Drosophila Linker Histone H1.The Journal of biological chemistry · 2016Article
- Role of H1 linker histones in mammalian development and stem cell differentiation.Biochimica et biophysica acta · 2016Review
- Local compartment changes and regulatory landscape alterations in histone H1-depleted cells.Genome biology · 2015Article
- H2A.Z/H2B.Z double-variant nucleosomes inhabit the AT-rich promoter regions of the Plasmodium falciparum genome.Molecular microbiology · 2013Article
- Polymorphism in a histone H1 subtype with a short N-terminal domain in three legume species (Fabaceae, Fabaeae).Molecular biology reports · 2012Article
- Nucleosome interaction surface of linker histone H1c is distinct from that of H1(0).The Journal of biological chemistry · 2010Article
- HistoneHits: a database for histone mutations and their phenotypes.Genome research · 2009Article
- Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth.PLoS genetics · 2008Article
- Article
- Global dynamics of newly constructed oligonucleosomes of conventional and variant H2A.Z histone.BMC structural biology · 2007Article
- Mass spectrometry-based strategies for characterization of histones and their post-translational modifications.Expert review of proteomics · 2007Review
- Article
- Constitutive expression exposes functional redundancy between the Arabidopsis histone H2A gene HTA1 and other H2A gene family members.The Plant cell · 2006Article
- A new family of "H3L-like" histone genes.Journal of molecular evolution · 2004Article
- Mining core histone sequences from public protein databases.Methods in enzymology · 2004Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In most eukaryotes, histones, which are the major structural components of chromatin, are expressed as a family of sequence variants encoded by multiple genes. Because different histone variants can contribute to a distinct or unique nucleosomal architecture, this heterogeneity can be exploited to regulate a wide range of nuclear functions, and evidence is accumulating that histone variants do indeed have distinct functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.