ArticleIntensive care medicine2001
Differential indication for mechanical circulatory support following heart transplantation.
Article in Intensive care medicine, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 48 citations in OpenAlex.
- Predictors of successful extracorporeal membrane oxygenation (ECMO) weaning after assistance for refractory cardiogenic shock.Intensive care medicine · 2011Trial
- Extracorporeal rescue for early and late graft failure after cardiac transplantation: short result and long-term followup.TheScientificWorldJournal · 2013Article
- Should heart transplant recipients with early graft failure be considered for retransplantation?The Annals of thoracic surgery · 2011Article
- Mechanical circulatory support with the ABIOMED BVS 5000: the Toronto General Hospital experience.The Canadian journal of cardiology · 2010Article
- Management of acute severe perioperative failure of cardiac allografts: a single-centre experience with a review of the literature.The Canadian journal of cardiology · 2007Review
- Perioperative pharmacotherapy in patients with left ventricular assist devices.Drugs & aging · 2004Review
- Mechanical circulatory support: expanding knowledge and experience in a challenging patient subset.Intensive care medicine · 2001Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe describe our experience with ventricular assist devices (VAD) in patients with cardiogenic shock refractory to pharmacological therapy and support using intraaortic balloon pump after cardiac transplantation. PATIENTS: Between July 1987 and August 1997, 848 patients underwent cardiac transplantation in our hospital.
interventionsFifteen patients (1.8%) needed mechanical circulatory support for refractory cardiac failure due to right heart failure (six patients), primary graft failure (three patients), and acute rejection (six patients). Three pump systems were used: Biomedicus Centrifugal Pump, Abiomed BVS 500, and Thoratec VAD. The choice of system depended on the indication and quality of each device. Seven patients (47%) could be weaned from the mechanical circulatory support (MCS) system and three patients (20%) are long-term survivors.
resultsAll 15 patients developed at least one serious complication, such as multiorgan failure (MOF), liver failure, acute renal failure or sepsis. Twenty-five per cent had severe bleeding and 13% had neurological complication. Mortality was due mostly to MOF, MOF and sepsis or sepsis. The survivors had a CI greater than 2.2 l.min.m2, total bilirubin less than 1.0 U/1, and did not undergo resuscitation.
conclusionsHeart failure after cardiac transplantation severe enough to require MCS is currently associated with several major complications and high mortality (80%).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.