ArticleBiophysical journal2001
Controlling the direction of kinesin-driven microtubule movements along microlithographic tracks.
Article in Biophysical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Actomyosin-Based Nanodevices for Sensing and Actuation: Bridging Biology and Bioengineering.Biosensors · 2025Review
- Active spiralling of microtubules driven by kinesin motors.Scientific reports · 2025Article
- Surface Topography Induces and Orients Nematic Swarms of Active Filaments: Considerations for Lab-On-A-Chip Devices.ACS applied nano materials · 2024Article
- Nanolithographic Fabrication Technologies for Network-Based Biocomputation Devices.Materials (Basel, Switzerland) · 2023Article
- Through the Eyes of Creators: Observing Artificial Molecular Motors.ACS nanoscience Au · 2022Review
- Protein Based Biomaterials for Therapeutic and Diagnostic Applications.Progress in biomedical engineering (Bristol, England) · 2022Article
- A bio-pen for direct writing of single molecules on user-functionalized surfaces.Nanoscale advances · 2020Article
- Magnetic Cytoskeleton Affinity Purification of Microtubule Motors Conjugated to Quantum Dots.Bioconjugate chemistry · 2018Article
- Non-equilibrium assembly of microtubules: from molecules to autonomous chemical robots.Chemical Society reviews · 2017Review
- Sensing surface mechanical deformation using active probes driven by motor proteins.Nature communications · 2016Article
- On-chip microtubule gliding assay for parallel measurement of tau protein species.Lab on a chip · 2016Article
- Parallel computation with molecular-motor-propelled agents in nanofabricated networks.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Control of microtubule trajectory within an electric field by altering surface charge density.Scientific reports · 2015Article
- Negative differential electrical resistance of a rotational organic nanomotor.Beilstein journal of nanotechnology · 2015Article
- Tug-of-war of microtubule filaments at the boundary of a kinesin- and dynein-patterned surface.Scientific reports · 2014Article
- Transport and self-organization across different length scales powered by motor proteins and programmed by DNA.Nature nanotechnology · 2014Article
- Self-organized optical device driven by motor proteins.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Magnetic capture from blood rescues molecular motor function in diagnostic nanodevices.Journal of nanobiotechnology · 2013Article
- Article
- Tracking actomyosin at fluorescence check points.Scientific reports · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor proteins are able to move protein filaments in vitro. However, useful work cannot be extracted from the existing in vitro systems because filament motions are in random directions on two-dimensional surfaces. We succeeded in restricting kinesin-driven movements of microtubules along linear tracks by using micrometer-scaled grooves lithographically fabricated on glass surfaces. We also accomplished the extraction of unidirectional movement from the bidirectional movements along the linear tracks by adding arrowhead patterns on the tracks. These "rectifiers" enabled us to construct microminiturized circulators in which populations of microtubules rotated in one direction, and to actively transport microtubules between two pools connected by arrowheaded tracks in the fields of micrometer scales.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.