ArticleDigestive diseases and sciences2001
Effect of ischemia-reperfusion on bile canalicular F-actin microfilaments in hepatocytes of human liver allograft: image analysis by confocal laser scanning microscopy.
Article in Digestive diseases and sciences, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Blood-Bile Barrier: Morphology, Regulation, and Pathophysiology.Gene expression · 2019Review
- The Landscape of Digital Pathology in Transplantation: From the Beginning to the Virtual E-Slide.Journal of pathology informatics · 2019Review
- Effect of HSP27 and Cofilin in the injury of hypoxia/reoxygenation on hepatocyte membrane F-actin microfilaments.Medicine · 2017Observational
- Hepatocellular carcinoma-targeted drug discovery through image-based phenotypic screening in co-cultures of HCC cells with hepatocytes.BMC cancer · 2016Article
- Polyethylene Glycol Preconditioning: An Effective Strategy to Prevent Liver Ischemia Reperfusion Injury.Oxidative medicine and cellular longevity · 2016Article
- Polyethylene glycol rinse solution: an effective way to prevent ischemia-reperfusion injury.World journal of gastroenterology · 2014Article
- Aetiology and risk factors of ischaemic cholangiopathy after liver transplantation.World journal of gastroenterology · 2014Review
- Fed state prior to hemorrhagic shock and polytrauma in a porcine model results in altered liver transcriptomic response.PloS one · 2014Article
- Bile duct epithelial tight junctions and barrier function.Tissue barriers · 2013Review
- Canine liver transplantation model and the intermediate filaments of the cytoskeleton of the hepatocytes.Journal of biomedicine & biotechnology · 2012Review
- Human heat shock protein 27-overexpressing mice are protected against acute kidney injury after hepatic ischemia and reperfusion.American journal of physiology. Renal physiology · 2009Article
- Human heat shock protein 27 overexpressing mice are protected against hepatic ischemia and reperfusion injury.Transplantation · 2009Article
- Ischemic preconditioning and intermittent ischemia preserve bile flow in a rat model of ischemia/reperfusion injury.Digestive diseases and sciences · 2007Article
- Ischemic preconditioning and intermittent ischemia preserve bile flow in a rat model of ischemia reperfusion injury.Digestive diseases and sciences · 2007Article
- Proteomic analysis of tyrosine phosphorylation during human liver transplantation.Proteome science · 2007Article
- Hepatic ischemia-reperfusion injury: roles of Ca2+ and other intracellular mediators of impaired bile flow and hepatocyte damage.Digestive diseases and sciences · 2006Review
- Effect of ischemia-reperfusion on Na+, K+-ATPase expression in human liver tissue allograft: image analysis by confocal laser scanning microscopy.Digestive diseases and sciences · 2004Article
- Expression of intercellular adhesion molecule-1 (ICAM- 1) during ischemia-reperfusion in human liver tissue allograft: image analysis by confocal laser scanning microscopy.Digestive diseases and sciences · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We studied and quantified the effect of ischemia-reperfusion on hepatic F-actin on bile canalicular and basolateral membranes in human liver allografts by means of confocal laser scanning microscopy imaging. The phalloidin-FITC staining of F-actin was normal in liver hepatocytes before reperfusion but decreased significantly after reperfusion (by 25% of controls). These results indicate that hepatic F-actin alteration is produced during the reperfusion phase. This modification, probably induced by reactive oxygen species, could impair bile canalicular contraction and tight junction permeability and consequently bile secretion in the postoperative period.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.