ArticlePlant physiology2001
Aluminum inhibits the H(+)-ATPase activity by permanently altering the plasma membrane surface potentials in squash roots.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 130 citations in OpenAlex.
- The Role of Low-Molecular-Weight Organic Acids in Metal Homeostasis in Plants.International journal of molecular sciences · 2024Review
- Gibberellin-Mediated Sensitivity of Rice Roots to Aluminum Stress.Plants (Basel, Switzerland) · 2024Article
- PP2C.D phosphatase SAL1 positively regulates aluminum resistance via restriction of aluminum uptake in rice.Plant physiology · 2023Article
- A Defective Vacuolar Proton Pump Enhances Aluminum Tolerance by Reducing Vacuole Sequestration of Organic Acids.Plant physiology · 2019Article
- Aluminum, a Friend or Foe of Higher Plants in Acid Soils.Frontiers in plant science · 2017Review
- The Role of the Plasma Membrane HFrontiers in plant science · 2017Review
- Arsenic stress affects the expression profile of genes of 14-3-3 proteins in the shoot of mycorrhiza colonized rice.Physiology and molecular biology of plants : an international journal of functional plant biology · 2016Article
- Aluminium-induced reduction of plant growth in alfalfa (Medicago sativa) is mediated by interrupting auxin transport and accumulation in roots.Scientific reports · 2016Article
- Alteration of Zeta potential and membrane permeability in bacteria: a study with cationic agents.SpringerPlus · 2015Article
- Roles of organic acid anion secretion in aluminium tolerance of higher plants.BioMed research international · 2013Review
- Getting to the roots of it: Genetic and hormonal control of root architecture.Frontiers in plant science · 2013Article
- Structural changes in MSymbiosis (Philadelphia, Pa.) · 2012Article
- Aluminum regulates oxalate secretion and plasma membrane H+-ATPase activity independently in tomato roots.Planta · 2011Article
- The role of the root apoplast in aluminium-induced inhibition of root elongation and in aluminium resistance of plants: a review.Annals of botany · 2010Review
- Aluminium-induced ion transport in Arabidopsis: the relationship between Al tolerance and root ion flux.Journal of experimental botany · 2010Article
- STOP1 regulates multiple genes that protect arabidopsis from proton and aluminum toxicities.Plant physiology · 2009Article
- The plasma membrane H+-ATPase is related to the development of salicylic acid-induced thermotolerance in pea leaves.Planta · 2009Article
- Aluminum toxicity and Ca depletion may enhance cell death of tobacco cells via similar syndrome.Plant signaling & behavior · 2008Article
- The role of the plasma membrane in the response of plant roots to aluminum toxicity.Plant signaling & behavior · 2006Article
- Citrate secretion coupled with the modulation of soybean root tip under aluminum stress. Up-regulation of transcription, translation, and threonine-oriented phosphorylation of plasma membrane H+-ATPase.Plant physiology · 2005Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although aluminum (AL) toxicity has been widely studied in monocotyledonous crop plants, the mechanism of Al impact on economically important dicotyledonous plants is poorly understood. Here, we report the spatial pattern of Al-induced root growth inhibition, which is closely associated with inhibition of H(+)-ATPase activity coupled with decreased surface negativity of plasma membrane (PM) vesicles isolated from apical 5-mm root segments of squash (Cucurbita pepo L. cv Tetsukabuto) plants. High-sensitivity growth measurements indicated that the central elongation zone, located 2 to 4 mm from the tip, was preferentially inhibited where high Al accumulation was found. The highest positive shifts (depolarization) in zeta potential of the isolated PM vesicles from 0- to 5-mm regions of Al-treated roots were corresponded to pronounced inhibition of H(+)-ATPase activity. The depolarization of PM vesicles isolated from Al-treated roots in response to added Al in vitro was less than that of control roots, suggesting, particularly in the first 5-mm root apex, a tight Al binding to PM target sites or irreversible alteration of PM properties upon Al treatment to intact plants. In line with these data, immunolocalization of H(+)-ATPase revealed decreases in tissue-specific H(+)-ATPase in the epidermal and cortex cells (2--3 mm from tip) following Al treatments. Our report provides the first circumstantial evidence for a zone-specific depolarization of PM surface potential coupled with inhibition of H(+)-ATPase activity. These effects may indicate a direct Al interaction with H(+)-ATPase from the cytoplasmic side of the PM.
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