ArticleThe Plant cell2001
G2/M-phase-specific transcription during the plant cell cycle is mediated by c-Myb-like transcription factors.
Article in The Plant cell, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 102 papers.
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Who cites it
102 citing papers in PubMed, 222 citations in OpenAlex.
- A simple cell-cycle control system in Marchantia polymorpha provides a framework for understanding plant cell proliferation.The Plant cell · 2026Article
- smoppix: unified nonparametric analysis of single-molecule spatial omics data using probabilistic indices.Genome biology · 2026Article
- Overexpression of TgMYB2 from the teak MYB gene family impacts biomass accumulation and secondary cell wall in tobacco plants.Plant molecular biology · 2025Article
- Article
- Genome-wide identification and expression profiling of MYB transcription factors in Artemisia argyi.BMC genomics · 2025Article
- Functional studies of plant transcription factors and their relevance in the plant root-knot nematode interaction.Frontiers in plant science · 2024Review
- MYB3R-SCL28-SMR module with a role in cell size control negatively regulates G2 progression inPlant signaling & behavior · 2023Article
- MYB3R-mediated and cell cycle-dependent transcriptional regulation of a tobacco ortholog ofPlant biotechnology (Tokyo, Japan) · 2023Article
- Modelling how plant cell-cycle progression leads to cell size regulation.PLoS computational biology · 2023Article
- Characterization of Transcriptome Dynamics during Early Fruit Development in Olive (International journal of molecular sciences · 2023Article
- Comparative analysis of theFrontiers in plant science · 2023Article
- Genome editing of SlMYB3R3, a cell cycle transcription factor gene of tomato, induces elongated fruit shape.Journal of experimental botany · 2022Article
- Genome-Scale Identification, Classification, and Expression Profiling of MYB Transcription Factor Genes inInternational journal of molecular sciences · 2022Article
- Visualization of the Crossroads between a Nascent Infection Thread and the First Cell Division Event inInternational journal of molecular sciences · 2022Article
- A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis.Nature communications · 2022Article
- Cis-acting elements involved in the G2/M-phase-specific transcription of the cyclin B gene in the unicellular alga Cyanidioschyzon merolae.Journal of plant research · 2021Article
- Concerted control of the LaRAV1-LaCDKB1;3 module by temperature during dormancy release and reactivation of larch.Tree physiology · 2021Article
- Genome-wide analysis of R2R3-MYB transcription factors family in the autopolyploid Saccharum spontaneum: an exploration of dominance expression and stress response.BMC genomics · 2021Article
- Identification of two tobacco genes encoding MYB3R proteins with repressor function and showing cell cycle-regulated transcript accumulation.Plant biotechnology (Tokyo, Japan) · 2021Article
- Genome-wide identification and functional characterization of the PheE2F/DP gene family in Moso bamboo.BMC plant biology · 2021Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant B-type cyclin genes are expressed specifically in late G2- and M-phases during the cell cycle. Their promoters contain a common cis-acting element, called the MSA (M-specific activator) element, that is necessary and sufficient for periodic promoter activation. This motif also is present in the tobacco kinesin-like protein gene NACK1, which is expressed with timing similar to that of B-type cyclin genes. In this study, we show that G2/M-phase-specific activation of the NACK1 promoter also is regulated by the MSA element, suggesting that a defined set of G2/M-phase-specific genes are coregulated by an MSA-mediated mechanism. In a search for MSA binding factors by yeast one-hybrid screening, we identified three different Myb-like proteins that interact specifically with the MSA sequence. Unlike the majority of plant Myb-like proteins, these Myb proteins, NtmybA1, NtmybA2, and NtmybB, have three imperfect repeats in the DNA binding domain, as in animal c-Myb proteins. During the cell cycle, the level of NtmybB mRNA did not change significantly, whereas the levels of NtmybA1 and A2 mRNAs fluctuated and peaked at M-phase, when B-type cyclin genes were maximally induced. In transient expression assays, NtmybA1 and A2 activated the MSA-containing promoters, whereas NtmybB repressed them. Furthermore, expression of NtmybB repressed the transcriptional activation mediated by NtmybA2. Our data show that a group of plant Myb proteins that are structurally similar to animal c-Myb proteins have unexpected roles in G2/M-phase by modulating the expression of B-type cyclin genes and may regulate a suite of coexpressed genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.