Evidence map›Paper›PMID 11487275›Full record

ArticleBritish journal of cancer2001

CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation.

C Jones, A V Nonni, L Fulford, S Merrett, R Chaggar, V Eusebi, S R Lakhani

Open access · hybridAbstract readComparative Study
In one paragraph

Article in British journal of cancer, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 132 citations in OpenAlex.

  1. Article
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  11. Androgen receptor is frequently expressed in HER2-positive, ER/PR-negative breast cancers.Virchows Archiv : an international journal of pathology · 2010
    Article
  12. Review
  13. Article
  14. Article
  15. Demystifying basal-like breast carcinomas.Journal of clinical pathology · 2007
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

C JonesThe Ludwig Institute for Cancer Research/UCL Breast Molecular Pathology Group, Royal Free & University College Medical School, UK.
A V Nonni
L Fulford
S Merrett
R Chaggar
V Eusebi
S R Lakhani
The Royal Free Hospital · GBUniversity College London · GBUniversity of Bologna · ITUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2-18% of ductal carcinoma-No Special Type (NST) are reported to express basal cell keratin 14 and such tumours may have a different metastatic pattern and prognosis. We performed immunohistochemistry for cytokeratins 19 (luminal) and 14 (basal) on 92 ductal carcinoma-NST. Those tumours showing CK14 expression were further characterized by immunohistochemistry for myoepithelial cell phenotype and analysed by comparative genomic hybridization. The 7 cases of ductal carcinoma-NST exhibiting a basal cell phenotype were all grade III tumours and showed a molecular cytogenetic profile similar to more conventional myoepithelial cell carcinomas. Therefore it appears that grade III invasive ductal carcinomas contain a subset of tumours with specific morphological and cytogenetic characteristics, and probably prognosis for the patient.

Indexed as

AdultAgedAged, 80 and overBasal Cell CarcinomaBiomarkers, TumorBreast NeoplasmsCarcinoma, Ductal, BreastCell DifferentiationHumansImmunoenzyme TechniquesKeratinsMaleMiddle AgedMyoepitheliomaNeoplasm ProteinsNeoplasm StagingBiomarkers, TumorKeratinsNeoplasm Proteins

Identifiers

PMID11487275
PMCPMC2364069
OpenAlexW1930849536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.