Evidence map›Paper›PMID 11483584›Full record

ArticleGenome research2001

Creating the gene ontology resource: design and implementation.

Gene Ontology Consortium

Abstract read
In one paragraph

Article in Genome research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 408 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
408citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

408 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Identification of Changes in Gene Expression.Biometrical journal. Biometrische Zeitschrift · 2026
    Article
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  7. Central Dogma Cycle and Network: A Model for Cell Memory.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
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348 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gene Ontology Consortium

Funding

SOFTWARE AND DATABASE SYSTEM DEVELOPMENTP41HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1995 to 2010
$72.1M
FLYBASE: A DROSOPHILA RELATIONAL DATABASEP41HG000739 · NHGRI · HARVARD UNIVERSITY · PI GELBART, WILLIAM MARTIN · 1992 to 2014
$56.6M
Resource ProjectU41HG002273 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, PAUL D. · 2012 to 2021
$34.7M
Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
Gene Ontology ConsortiumP41HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2004 to 2011
$27.4M
GENOMIC DATABASE FOR THE YEAST SACCHAROMYCESP41HG001315 · NHGRI · STANFORD UNIVERSITY · PI CHERRY, J. MICHAEL · 1995 to 2010
$27.1M
Genomic Resource for the Yeast SaccharomycesU41HG001315 · NHGRI · STANFORD UNIVERSITY · PI CHERRY, J. MICHAEL · 2011 to 2020
$26.4M
GENE EXPRESSION DATABASE FOR MOUSE DEVELOPMENTR01HD033745 · NICHD · JACKSON LABORATORY · PI RINGWALD, MARTIN · 1996 to 2010
$10.9M
GENE ONTOLOGY CONSORTIUMR01HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2001 to 2003
$5.8M
NHGRI NIH HHS HG02273NHGRI NIH HHS P41 HG000330NHGRI NIH HHS P41 HG000739NHGRI NIH HHS P41 HG001315NHGRI NIH HHS P41 HG002273NHGRI NIH HHS P41 HG00330NHGRI NIH HHS P41 HG00739NHGRI NIH HHS P41 HG01315NHGRI NIH HHS R01 HG002273NHGRI NIH HHS U41 HG000739NHGRI NIH HHS U41 HG001315NHGRI NIH HHS U41 HG002273NICHD NIH HHS HD33745NICHD NIH HHS R01 HD033745
6 · The paper itself

Abstract

The exponential growth in the volume of accessible biological information has generated a confusion of voices surrounding the annotation of molecular information about genes and their products. The Gene Ontology (GO) project seeks to provide a set of structured vocabularies for specific biological domains that can be used to describe gene products in any organism. This work includes building three extensive ontologies to describe molecular function, biological process, and cellular component, and providing a community database resource that supports the use of these ontologies. The GO Consortium was initiated by scientists associated with three model organism databases: SGD, the Saccharomyces Genome database; FlyBase, the Drosophila genome database; and MGD/GXD, the Mouse Genome Informatics databases. Additional model organism database groups are joining the project. Each of these model organism information systems is annotating genes and gene products using GO vocabulary terms and incorporating these annotations into their respective model organism databases. Each database contributes its annotation files to a shared GO data resource accessible to the public at http://www.geneontology.org/. The GO site can be used by the community both to recover the GO vocabularies and to access the annotated gene product data sets from the model organism databases. The GO Consortium supports the development of the GO database resource and provides tools enabling curators and researchers to query and manipulate the vocabularies. We believe that the shared development of this molecular annotation resource will contribute to the unification of biological information.

Indexed as

GenesAnimalsCaenorhabditis elegansComputational BiologyDatabases, FactualDrosophilaGenes, FungalGenes, HelminthGenes, InsectGenes, PlantMiceOnline SystemsSaccharomycesTerminology as Topic

Identifiers

PMID11483584
PMCPMC311077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.