ArticleProceedings of the National Academy of Sciences of the United States of America2001
The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.
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116 citing papers in PubMed, 305 citations in OpenAlex.
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- A minimized symbiotic gene set from the 1.68 Mb pSymB chromid of Sinorhizobium meliloti reveals auxiliary symbiotic loci.BMC biology · 2025Article
- Completed genomes fromCurrent research in microbial sciences · 2025Article
- Elevated Rates of Molecular Evolution Genome-wide in Mutualist Legumes and Rhizobia.Molecular biology and evolution · 2024Article
- tRNA queuosine modification is involved in biofilm formation and virulence in bacteria.Nucleic acids research · 2023Article
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- In-depth genome analysis of Bacillus sp. BH32, a salt stress-tolerant endophyte obtained from a halophyte in a semiarid region.Applied microbiology and biotechnology · 2022Article
- The Genome of the Acid Soil-Adapted StrainFrontiers in microbiology · 2022Article
- Identification of a Novel Pyruvyltransferase UsingJournal of bacteriology · 2021Article
- Rhizobial Exopolysaccharides: Genetic Regulation of Their Synthesis and Relevance in Symbiosis with Legumes.International journal of molecular sciences · 2021Review
- Minimal gene set fromProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Co-catabolism of arginine and succinate drives symbiotic nitrogen fixation.Molecular systems biology · 2020Article
- Isolation, Biochemical and Genomic Characterization of Glyphosate Tolerant Bacteria to Perform Microbe-Assisted Phytoremediation.Frontiers in microbiology · 2020Article
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- Genome-wide identification of genes directly regulated by ChvI and a consensus sequence for ChvI binding in Sinorhizobium meliloti.Molecular microbiology · 2018Article
- Maintenance of multipartite genome system and its functional significance in bacteria.Journal of genetics · 2018Review
- The complete replicons of 16 Ensifer meliloti strains offer insights into intra- and inter-replicon gene transfer, transposon-associated loci, and repeat elements.Microbial genomics · 2018Article
56 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Analysis of the 1,683,333-nt sequence of the pSymB megaplasmid from the symbiotic N(2)-fixing bacterium Sinorhizobium meliloti revealed that the replicon has a high gene density with a total of 1,570 protein-coding regions, with few insertion elements and regions duplicated elsewhere in the genome. The only copies of an essential arg-tRNA gene and the minCDE genes are located on pSymB. Almost 20% of the pSymB sequence carries genes encoding solute uptake systems, most of which were of the ATP-binding cassette family. Many previously unsuspected genes involved in polysaccharide biosynthesis were identified and these, together with the two known distinct exopolysaccharide synthesis gene clusters, show that 14% of the pSymB sequence is dedicated to polysaccharide synthesis. Other recognizable gene clusters include many involved in catabolic activities such as protocatechuate utilization and phosphonate degradation. The functions of these genes are consistent with the notion that pSymB plays a major role in the saprophytic competence of the bacteria in the soil environment.
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