ArticleNucleic acids research2001
Dynamics of association of origins of DNA replication with the nuclear matrix during the cell cycle.
Article in Nucleic acids research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 40 citations in OpenAlex.
- The Protective Role of Dormant Origins in Response to Replicative Stress.International journal of molecular sciences · 2018Review
- Article
- Relationship between DNA replication and the nuclear matrix.Genes to cells : devoted to molecular & cellular mechanisms · 2013Review
- Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.Nucleic acids research · 2011Article
- Nuclear scaffold attachment sites within ENCODE regions associate with actively transcribed genes.PloS one · 2011Article
- DNA moves sequentially towards the nuclear matrix during DNA replication in vivo.BMC cell biology · 2011Article
- DNA is a co-factor for its own replication in Xenopus egg extracts.Nucleic acids research · 2011Article
- Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro.Journal of cell science · 2010Article
- Modulation of chromatin by MARs and MAR binding oncogenic transcription factor SMAR1.Molecular and cellular biochemistry · 2010Article
- Anchoring the genome.Genome biology · 2008Review
- The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture.Chromosoma · 2005Review
- Comparison of nuclear matrix proteins between gastric cancer and normal gastric tissue.World journal of gastroenterology · 2004Article
- The human beta-globin replication initiation region consists of two modular independent replicators.Molecular and cellular biology · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA of replication foci attached to the nuclear matrix was isolated from Chinese hamster ovary cells and human HeLa cells synchronized at different stages of the G(1) and S phases of the cell cycle. The abundance of sequences from dihydrofolate reductase ori-beta and the beta-globin replicator was determined in matrix-attached DNA. The results show that matrix-attached DNA isolated from cells in late G(1) phase was enriched in origin sequences in comparison with matrix-attached DNA from early G(1) phase cells. The concentration of the early firing ori-beta in DNA attached to the matrix decreased in early S phase, while the late firing beta-globin origin remained attached until late S phase. We conclude that replication origins associate with the nuclear matrix in late G(1) phase and dissociate after initiation of DNA replication in S phase.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.