Evidence map›Paper›PMID 11470031›Full record

ArticleCurrent infectious disease reports2001

Perinatal Transmission of HIV: Recognition and Treatment Interventions.

Jaime Deville, Yvonne Bryson

Abstract read
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In one paragraph

Article in Current infectious disease reports, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jaime DevilleUCLA School of Medicine, Mattel Children's Hospital, 10833 Le Conte Avenue, 22-442 MDCC, Los Angeles, CA 90095-1752, USA. ybryson@mednet.ucla.edu; jdeville@mednet.ucla.edu
Yvonne Bryson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Great strides have been made in the fight against vertical transmission of HIV-1. Improved understanding of mechanisms and timing of transmission of HIV-1 from mother to child have led to the development of effective intervention strategies that have reduced transmission rates to unprecedented low levels, below 2% in developed countries. New reports using shortened, more affordable courses of antiretrovirals prenatally or at the time of delivery have also shown a significant reduction in transmission, over 50% in studies conducted in the developing world. These advances, combined with ongoing studies using simplified effective treatment regimens, have made possible the potential to significantly reduce perinatal transmission worldwide. Future challenges include reduction of breast feeding transmission and the development of an effective HIV-1 vaccine to produce long-lasting protection.

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.