Evidence map›Paper›PMID 11468957›Full record

ReviewCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2001

Variant Creutzfeldt-Jakob disease: a summary of current scientific knowledge in relation to public health.

M B Coulthart, N R Cashman

Abstract readReview
In one paragraph

Review in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Creutzfeldt-Jakob disease mortality in Canada, 1998 to 2013.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2015
    Article
  4. Article
  5. Review
  6. Article
  7. Wild game feasts and fatal degenerative neurologic illness.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2003
    Article
  8. Cell mediated immune responses against human prion protein.Clinical and experimental immunology · 2003
    Article
  9. Creutzfeldt-Jakob disease and infection control.The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses · 2001
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M B CoulthartNational Laboratory for Host Genetics and Prion Diseases, Canadian Science Centre for Human and Animal Health, Health Canada, Winnipeg, Man. mike_coulthart@hc-sc.gc.ca
N R Cashman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prion diseases pose unique scientific, medical, veterinary and regulatory challenges. Here, we summarize current information bearing on the natural history, pathobiology and epidemiology of these disorders and public policy responses to the potential threats to public health posed, particularly, by bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease (vCJD). Six years after the first case reports of vCJD, there is still no clear indication of the magnitude of the primary epidemic, or of the likelihood of lateral transmission of this untreatable disease by iatrogenic means, particularly by blood and blood products. However, the unsettling nature of the available evidence warrants prudence regarding public health policy and regulation, as well as a forward-looking approach to research.

Indexed as

Creutzfeldt-Jakob SyndromePublic HealthAnimalsCattleDisease OutbreaksEncephalopathy, Bovine SpongiformHealth PolicyHumansIncidencePopulation SurveillanceUnited KingdomZoonoses

Identifiers

PMID11468957
PMCPMC81246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.