ArticleJournal of bacteriology2001
YLR209c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase.
Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Scarless Genetic Engineering ofJournal of microbiology and biotechnology · 2025Article
- The Characterization of the Purine Nucleoside Phosphorylase fromJournal of fungi (Basel, Switzerland) · 2025Article
- Single nucleotide polymorphisms associated with wine fermentation and adaptation to nitrogen limitation in wild and domesticated yeast strains.Biological research · 2023Article
- Global mapping of protein-metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity.Communications biology · 2021Article
- Review
- Systems analysis of phosphate-limitation-induced lipid accumulation by the oleaginous yeastBiotechnology for biofuels · 2018Article
- Article
- Bulk RNA degradation by nitrogen starvation-induced autophagy in yeast.The EMBO journal · 2015Article
- Nucleotide degradation and ribose salvage in yeast.Molecular systems biology · 2013Article
- Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae.Genetics · 2012Article
- Control of ATP homeostasis during the respiro-fermentative transition in yeast.Molecular systems biology · 2010Article
- Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.The Journal of biological chemistry · 2009Article
- Article
- Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism.The Journal of biological chemistry · 2009Article
- Lethal accumulation of guanylic nucleotides in Saccharomyces cerevisiae HPT1-deregulated mutants.Genetics · 2008Article
- The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase.BMC biochemistry · 2003Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The yeast YLR209c (PNP1) gene encodes a protein highly similar to purine nucleoside phosphorylases. This protein specifically metabolized inosine and guanosine. Disruption of PNP1 led to inosine and guanosine excretion in the medium, thus showing that PNP1 plays an important role in the metabolism of these purine nucleosides in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.