GuidelineArchives of disease in childhood2001
An evidence and consensus based guideline for acute diarrhoea management.
Guideline in Archives of disease in childhood, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Lactose avoidance for young children with acute diarrhoea.The Cochrane database of systematic reviews · 2013Pooled it
- Antimotility agents for chronic diarrhoea in people with HIV/AIDS.The Cochrane database of systematic reviews · 2008Pooled it
- Isotonic is better than hypotonic saline for intravenous rehydration of children with gastroenteritis: a prospective randomised study.Archives of disease in childhood · 2006Trial
- A methodology for determining dosing recommendations for anticancer drugs in patients with reduced kidney function.EClinicalMedicine · 2025Review
- Identifying gaps and providing recommendations to address shortcomings in the investigation of acne sequelae by the Personalising Acne: Consensus of Experts panel.JAAD international · 2021Article
- Gaps and recommendations for clinical management of truncal acne from the Personalising Acne: Consensus of Experts panel.JAAD international · 2021Article
- Recommendations for rosacea diagnosis, classification and management: update from the global ROSacea COnsensus 2019 panel.The British journal of dermatology · 2020Article
- Diagnosis, management, and prevention of rotavirus gastroenteritis in children.BMJ (Clinical research ed.) · 2013Review
- Medical education content required for kernicterus risk recognition.Iranian journal of pediatrics · 2012Article
- Normal saline is a safe initial rehydration fluid in children with diarrhea-related hypernatremia.European journal of pediatrics · 2012Article
- Guidelines on acute gastroenteritis in children: a critical appraisal of their quality and applicability in primary care.BMC family practice · 2011Article
- Evaluation of the quality of guidelines for acute gastroenteritis in children with the AGREE instrument.Journal of pediatric gastroenterology and nutrition · 2011Article
- Acute infectious diarrhea in children.Deutsches Arzteblatt international · 2009Review
- Manchester triage system in paediatric emergency care: prospective observational study.BMJ (Clinical research ed.) · 2008Article
- Developing and introducing evidence based clinical practice guidelines for serious illness in Kenya.Archives of disease in childhood · 2008Article
- [Acute dehydration in infant].Journal de pediatrie et de puericulture · 2008Article
- How has research changed my practice in the last 5 years?Archives of disease in childhood · 2007Article
- Is hyperchloraemic acidosis a problem in children with gastroenteritis rehydrated with normal saline? Authors' reply.Archives of disease in childhood · 2007Article
- [Acute infectious diarrhea].Presse medicale (Paris, France : 1983) · 2007Review
- Best practice in primary care pathology: review 6.Journal of clinical pathology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo develop an evidence and consensus based guideline for the management of the child who presents to hospital with diarrhoea (with or without vomiting), a common problem representing 16% of all paediatric medical attenders at an accident and emergency department. Clinical assessment, investigations (biochemistry and stool culture in particular), admission, and treatment are addressed. The guideline aims to aid junior doctors in recognising children who need admission for observation and treatment and those who may safely go home. EVIDENCE: A systematic review of the literature was performed. Selected articles were appraised, graded, and synthesised qualitatively. Statements on recommendation were generated. CONSENSUS: An anonymous, postal Delphi consensus process was used. A panel of 39 selected medical and nursing staff were asked to grade their agreement with the generated statements. They were sent the papers, appraisals, and literature review. On the second and third rounds they were asked to re-grade their agreement in the light of other panelists' responses. Consensus was predefined as 83% of panelists agreeing with the statement. RECOMMENDATIONS: Clinical signs useful in assessment of level of dehydration were agreed. Admission to a paediatric facility is advised for children who show signs of dehydration. For those with mild to moderate dehydration, estimated deficit is replaced over four hours with oral rehydration solution (glucose based, 200-250 mOsm/l) given "little and often". A nasogastric tube should be used if fluid is refused and normal feeds started following rehydration. Children at high risk of dehydration should be observed to ensure at least maintenance fluid is tolerated. Management of more severe dehydration is detailed. Antidiarrhoeal medication is not indicated. VALIDATION: The guideline has been successfully implemented and evaluated in a paediatric accident and emergency department.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.