ArticleSexually transmitted infections2001
The interrelation of HIV, cervical human papillomavirus, and neoplasia among antenatal clinic attenders in Tanzania.
Article in Sexually transmitted infections, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Identification of Genetic Variants of Human Papillomavirus in a Group of Mexican HIV/AIDS Patients and Their Possible Association with Cervical Cancer.Polish journal of microbiology · 2021Article
- Prevalence, risk factors, and pregnancy outcomes of cervical cell abnormalities in the puerperium in a hyperendemic HIV setting.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2018Article
- Prevalence and predictors of Cervical Intraepithelial Neoplasia among HIV infected women at Bugando Medical Centre, Mwanza-Tanzania.Infectious agents and cancer · 2013Article
- Prevalence, incidence and risk factors for anogenital warts in Sub Saharan Africa: a systematic review and meta analysis.Infectious agents and cancer · 2013Article
- Human papillomavirus seropositivity and subsequent risk of HIV acquisition in rural South African women.Sexually transmitted diseases · 2013Article
- Current treatment options for management of anal intraepithelial neoplasia.OncoTargets and therapy · 2013Article
- Risk factors for VIA positivity and determinants of screening attendances in Dar es Salaam, Tanzania.BMC public health · 2012Article
- HPV Type Distribution and Cervical Cytology among HIV-Positive Tanzanian and South African Women.ISRN obstetrics and gynecology · 2012Article
- HIV and cancer in Africa: mutual collaboration between HIV and cancer programs may provide timely research and public health data.Infectious agents and cancer · 2011Article
- Cervical cytology and histopathologic abnormalities in women living with AIDS in São Paulo, Brazil.Journal of acquired immune deficiency syndromes (1999) · 2011Article
- Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study.BMC infectious diseases · 2011Article
- Article
- Association of oncogenic and nononcogenic human papillomavirus with HIV incidence.Journal of acquired immune deficiency syndromes (1999) · 2010Article
- The status of cervical cytology in Swaziland, Southern Africa: a descriptive study.CytoJournal · 2009Article
- High-risk and multiple human papillomavirus (HPV) infections in cancer-free Jamaican women.Infectious agents and cancer · 2009Article
- Infection and cervical neoplasia: facts and fiction.International journal of clinical and experimental pathology · 2009Article
- Prevalence and predictors of high-risk human papillomavirus infection in a population-based sample of women in rural Uganda.International journal of STD & AIDS · 2008Article
- Cervical human papillomavirus infection in accra, ghana.Ghana medical journal · 2008Article
- The viral etiology of AIDS-associated malignancies.Advances in pharmacology (San Diego, Calif.) · 2008Review
- Human papillomavirus genotype distribution and cervical squamous intraepithelial lesions among high-risk women with and without HIV-1 infection in Burkina Faso.British journal of cancer · 2006Article
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11 authors.
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Abstract
objectivesTo determine the prevalence and interrelation of cervical human papillomavirus (HPV) genotypes, squamous intraepithelial lesions (SIL), HIV, and other reproductive tract infections (RTIs) among urban antenatal clinic attenders in Mwanza, Tanzania.
methodsGenital swabs were collected from 660 pregnant women and tested for a range of RTIs and for cervical cytology. Cervical HPV-DNA was detected by PCR and genotyped. HIV and syphilis serologies were performed.
resultsHPV prevalence was 34% (209/612 women). Of the 144 typeable samples, 83% were high risk (HR-HPV) oncogenic strains (56% HPV 16 related types). SIL was detected in 43 women (7%), with high grade SIL in 3%. There was a high prevalence of HIV (15%), and of any RTI (83%). Genital warts were detected in 20 women (3%). HPV infection was associated with some behavioural factors (short duration of relationship, single status, not using condoms) and gonorrhoea. There was no overall association between HPV and HIV (OR=1.02, 95% CI 0.6-1.6), but a non-significant trend towards a stronger association with HR-HPV in women aged 15-19 (OR=2.79, 95% CI 0.8-9.5) and women aged > or =30 (OR=3.20, 95% CI 0.7-15). SIL was associated with HPV (OR=3.66, 95% CI 1.9-7.0), but not significantly with HIV (OR=1.54, 95% CI 0.7-3.4). Prevalence of SIL was higher among women dually positive for HPV/HIV compared to HPV infection only (21% v 12%), although this difference was not statistically significant (p=0.17).
conclusionsHPV infection was highly prevalent in this young antenatal population. The association of HIV with HR-HPV types in older women may suggest that the principal HIV/HPV interaction in this population is for HIV to upregulate HPV persistence, leading to subsequent development of SIL.
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