ReviewJournal of the Royal Society of Medicine2001
Aldosterone as a determinant of cardiovascular and renal dysfunction.
Review in Journal of the Royal Society of Medicine, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00291720 (Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?), which is not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?
Who cites it
16 citing papers in PubMed.
- Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate.Diabetologia · 2004Trial
- Plasma aldosterone concentration and valvular heart disease in hypertensive patients: a large cross-sectional study.Scientific reports · 2026Article
- Risk of Hypertension and Chronic Kidney Disease Following Aldosterone Dysregulation.American journal of hypertension · 2026Article
- Reduced Weight Gain with Pioglitazone vs Vildagliptin inDiabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner.The Journal of endocrinology · 2023Article
- Ultrasonographic Detected Adrenomegaly in Clinically Ill Cats: A Retrospective Study.Veterinary sciences · 2022Article
- Examination of the association of steroids with fluid accumulation in critically ill patients, considering the possibility of biases.Scientific reports · 2021Article
- Article
- An additive effect of eplerenone to ACE inhibitor on slowing the progression of diabetic nephropathy in the db/db mice.American journal of translational research · 2016Article
- Mineralocorticoid receptors in vascular function and disease.Molecular and cellular endocrinology · 2012Review
- Spironolactone use in heart failure patients with end-stage renal disease on hemodialysis: is it safe?Clinical cardiology · 2010Review
- Application of direct renin inhibition to chronic kidney disease.Cardiovascular drugs and therapy · 2010Review
- Arterial plasma vasopressin and aldosterone predict left ventricular mass in men who develop hypertension over 20 years.Journal of clinical hypertension (Greenwich, Conn.) · 2007Article
- Aldosterone-receptor antagonism and end-stage renal disease.Current hypertension reports · 2004Article
- Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders.Pflugers Archiv : European journal of physiology · 2003Article
- Aldosterone: a risk factor for vascular disease.Current hypertension reports · 2003Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.