ArticleJournal of neurology, neurosurgery, and psychiatry2001
Diagnostic investigation of patients with chronic polyneuropathy: evaluation of a clinical guideline.
Article in Journal of neurology, neurosurgery, and psychiatry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Causal inference regarding infectious aetiology of chronic conditions: a systematic review.PloS one · 2013Pooled it
- Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies.medRxiv : the preprint server for health sciences · 2025Article
- A Conceptual Model of Patient Experiences of Painful Diabetic Peripheral Neuropathy to Support Clinical Outcomes Assessment.Journal of pain research · 2025Article
- Toward a Useful and Cost-Effective Workup in Chronic Polyneuropathy: The EXPRESS Study Protocol.Neuroepidemiology · 2025Observational
- Knowledge gaps in diagnosing chronic polyneuropathy: Review of national guidelines.Journal of the peripheral nervous system : JPNS · 2024Review
- Expert opinion on screening, diagnosis and management of diabetic peripheral neuropathy: a multidisciplinary approach.Frontiers in endocrinology · 2024Review
- Review
- Diagnosis and management of patients with polyneuropathy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Review
- Peripheral polyneuropathy from electrodiagnostic tests: a 10-year etiology and neurophysiology overview.Arquivos de neuro-psiquiatria · 2022Observational
- Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management.Brain : a journal of neurology · 2021Review
- Electrodiagnostic tests are unlikely to change management in those with a known cause of typical distal symmetric polyneuropathy.Muscle & nerve · 2017Article
- Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine.Journal of clinical and diagnostic research : JCDR · 2017Article
- Vibration upshot of operating mechanical sewing machine: an insight into common peroneal nerve conduction study.Annals of occupational and environmental medicine · 2017Article
- Updates in diabetic peripheral neuropathy.F1000Research · 2016Review
- The epidemiology and risk factors of chronic polyneuropathy.European journal of epidemiology · 2016Review
- Mechanisms of distal axonal degeneration in peripheral neuropathies.Neuroscience letters · 2015Review
- Are human peripheral nerves sensitive to X-ray imaging?PloS one · 2015Article
- Burning feet in polycythemia vera - peripheral sensorimotor axonal neuropathy with erythromelalgia.International journal of general medicine · 2015Article
- Assessment of electromyograghic findings in peroneus tertius, tibialis posterior and dorsal interoseous pedis muscles in patients with axonal polyneuropathy.Advanced biomedical research · 2013Article
- Effect of age on the fractional anisotropy (FA) value of peripheral nerves and clinical significance of the age-corrected FA value for evaluating polyneuropathies.Neuroradiology · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective(1) To evaluate a clinical guideline for the diagnostic investigation of patients presenting with signs and symptoms (present for longer than 6 weeks) suggesting a chronic polyneuropathy. (2) To investigate the contribution of electrophysiological studies to a focused search for aetiology in these patients.
methodsA chart review was carried out of a consecutive group of outpatients in 1993-7 at a university department of neurology, with signs and symptoms suggesting a polyneuropathy in whom the diagnostic investigation had been carried out according to a recently introduced guideline. Diagnostic tests were performed and final diagnoses were made.
resultsUnnecessary investigations were carried out in 108 (51%) of 213 patients and too few tests in 23 (11%) of these patients. In 82 (48%) of the 172 patients who fulfilled the inclusion criteria neurophysiological tests did not contribute to the final diagnosis. Neurophysiological criteria for demyelination were fulfilled in only 13 (8%) of the 172 patients.
conclusionIn patients presenting with signs and symptoms of chronic polyneuropathy the number of tests in the diagnostic investigation can be considerably reduced. In patients with signs and symptoms of polyneuropathy, providing the clinical phenotype is typical, in the presence of diabetes mellitus, renal failure, HIV infection, alcoholism, or use of potentially neurotoxic drugs further investigations are non-contributory. The significance of electrophysiological studies in the investigation of patients with polyneuropathy is rather to separate sensorimotor neuropathies from pure sensory neuropathies than to distinguish between demyelinating and axonal neuropathies.
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