Evidence map›Paper›PMID 11458270›Full record

ReviewPathology oncology research : POR2001

Angiogenesis-dependent diseases and angiogenesis therapy.

J Tímár, B Döme, K Fazekas, A Janovics, S Paku

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pathology oncology research : POR, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Targeting Angiogenesis via Resolution of Inflammation.Cold Spring Harbor perspectives in medicine · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Frontiers in chemistry · 2021
    Review
  7. Article
  8. Review
  9. Necrosis in the Tumor Microenvironment and Its Role in Cancer Recurrence.Advances in experimental medicine and biology · 2020
    Review
  10. Vascular defects ofDisease models & mechanisms · 2019
    Article
  11. Review
  12. Review
  13. Article
  14. AAV-CRISPR/Cas9-Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro.Investigative ophthalmology & visual science · 2017
    Article
  15. Review
  16. Article
  17. Review
  18. Journal of pediatric oncology · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J TímárNational Institute of Oncology, Department of Tumor Progression Ráth Gy. U. 7-9., Budapest, H1122, Hungary. 36 1 224 8786, 36 1 224 8620. jtimar@oncol.hu
B Döme
K Fazekas
A Janovics
S Paku
National Institute of Oncology · HUSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of the molecular mechanisms of physiological vasculogenesis and pathological angiogenesis helped to recognize two classes of diseases: one where the therapeutic angiogenesis can repair the tissue damages (arteriosclerosis, myocardial infarction, limb ischemia) and the other one where inhibition of pathological angiogenesis can cure the disease or delay its progression (retinopathies, benign and malignant angiogenic tumors, progression of malignant tumors). Although there are an exponentially growing number of new synthetic molecules characterized mainly by antiangiogenic properties, the discovery of a large battery of natural pro- and anti-angiogenic factors suggests that this may provide a more physiological approach to treat both class of angiogenesis-dependent diseases in the near future.

Indexed as

Angiogenesis InhibitorsAnimalsArteriosclerosisChick EmbryoCollateral CirculationEndothelial Growth FactorsEndothelium, VascularHumansLymphokinesNeoplasmsNeovascularization, PathologicRetinal DiseasesSarcoma, KaposiSignal TransductionTelangiectasia, Hereditary HemorrhagicVascular Endothelial Growth Factor AAngiogenesis InhibitorsEndothelial Growth FactorsLymphokinesVascular Endothelial Growth Factor AVascular Endothelial Growth Factors

Identifiers

PMID11458270
OpenAlexW2119656796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.