ArticleGenetics2001
Multiple losses and transfers to the nucleus of two mitochondrial succinate dehydrogenase genes during angiosperm evolution.
Article in Genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.
- A Systematic Review and Developmental Perspective on Origin of CMS Genes in Crops.International journal of molecular sciences · 2024Pooled it
- The cytonuclear interactions during grapevine domestication.Journal of integrative plant biology · 2025Article
- Assembling genomes of non-model plants: A case study with evolutionary insights from Ranunculus (Ranunculaceae).The Plant journal : for cell and molecular biology · 2025Article
- Complete mitochondrial genome of Polygonatum cyrtonema Hua reveals variation diversity and evolutionary trends.BMC plant biology · 2025Article
- Characterize the Complete Mitogenome ofEcology and evolution · 2025Article
- Comparative analysis of mitochondrial genomes ofFrontiers in plant science · 2023Article
- The mitochondrial genome sequence of Abies alba Mill. reveals a high structural and combinatorial variation.BMC genomics · 2022Article
- Discovery of succinate dehydrogenase candidate fungicides via lead optimization for effective resistance management of3 Biotech · 2022Article
- Complete mitogenomes of fourZooKeys · 2022Article
- Assembly and comparative analysis of the complete mitochondrial genome ofFrontiers in plant science · 2022Article
- Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome.BMC biology · 2021Article
- Single-cell genomics unveils a canonical origin of the diverse mitochondrial genomes of euglenozoans.BMC biology · 2021Article
- Mitochondrial Genome ofPlants (Basel, Switzerland) · 2020Article
- A functional twintron, 'zombie' twintrons and a hypermobile group II intron invading itself in plant mitochondria.Nucleic acids research · 2020Article
- The Mitochondrial Genome of Eleusine indica and Characterization of Gene Content within Poaceae.Genome biology and evolution · 2020Article
- Fluctuations in Fabaceae mitochondrial genome size and content are both ancient and recent.BMC plant biology · 2019Article
- PacBio-Based Mitochondrial Genome Assembly of Leucaena trichandra (Leguminosae) and an Intrageneric Assessment of Mitochondrial RNA Editing.Genome biology and evolution · 2018Article
- Assembly of the Mitochondrial Genome in the Campanulaceae Family Using Illumina Low-Coverage Sequencing.Genes · 2018Article
- The RNA Editing Factor SlORRM4 Is Required for Normal Fruit Ripening in Tomato.Plant physiology · 2017Article
- SDH6 and SDH7 Contribute to Anchoring Succinate Dehydrogenase to the Inner Mitochondrial Membrane in Arabidopsis thaliana.Plant physiology · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Unlike in animals, the functional transfer of mitochondrial genes to the nucleus is an ongoing process in plants. All but one of the previously reported transfers in angiosperms involve ribosomal protein genes. Here we report frequent transfer of two respiratory genes, sdh3 and sdh4 (encoding subunits 3 and 4 of succinate dehydrogenase), and we also show that these genes are present and expressed in the mitochondria of diverse angiosperms. Southern hybridization surveys reveal that sdh3 and sdh4 have been lost from the mitochondrion about 40 and 19 times, respectively, among the 280 angiosperm genera examined. Transferred, functional copies of sdh3 and sdh4 were characterized from the nucleus in four and three angiosperm families, respectively. The mitochondrial targeting presequences of two sdh3 genes are derived from preexisting genes for anciently transferred mitochondrial proteins. On the basis of the unique presequences of the nuclear genes and the recent mitochondrial gene losses, we infer that each of the seven nuclear sdh3 and sdh4 genes was derived from a separate transfer to the nucleus. These results strengthen the hypothesis that angiosperms are experiencing a recent evolutionary surge of mitochondrial gene transfer to the nucleus and reveal that this surge includes certain respiratory genes in addition to ribosomal protein genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.