ArticleGenetics2001
Structure and evolution of the hAT transposon superfamily.
Article in Genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
86 citing papers in PubMed, 176 citations in OpenAlex.
- Transposable elements hitchhike on Starships across fungal genomes.Nature communications · 2026Article
- Highly efficient transgenesis mediated by Tip100 transposon system in medaka.Transgenic research · 2025Article
- Divergent ECC1 effector homologs modulate host-specific virulence in cucurbit-infectingFrontiers in cellular and infection microbiology · 2025Article
- Characterization of hAT DNA transposon superfamily in the genome of Neotropical fish Apareiodon sp.Molecular genetics and genomics : MGG · 2024Article
- Genome-wide identification and characterization of SLEEPER, a transposon-derived gene family and their expression pattern in Brassica napus L.BMC plant biology · 2024Article
- Review
- The Initial Hepatitis B Virus-Hepatocyte Genomic Integrations and Their Role in Hepatocellular Oncogenesis.International journal of molecular sciences · 2023Review
- Independent evolution of transposase and TIRs facilitated by recombination betweenProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Jack of all trades versus master of one: how generalist versus specialist strategies of transposable elements relate to their horizontal transfer between lineages.Current opinion in genetics & development · 2023Review
- Identification and characterization of RuvBL DNA helicase genes for tolerance against abiotic stresses in bread wheat (Triticum aestivum L.) and related species.Functional & integrative genomics · 2023Article
- Article
- A New Hope: A Hermaphroditic Nematode Enables Analysis of a Recent Whole Genome Duplication Event.Genome biology and evolution · 2022Article
- Characterization of transposable elements within the Bemisia tabaci species complex.Mobile DNA · 2022Article
- Dissecting cricket genomes for the advancement of entomology and entomophagy.Biophysical reviews · 2022Review
- The widespread nature of Pack-TYPE transposons reveals their importance for plant genome evolution.PLoS genetics · 2022Article
- Article
- Article
- Characterization of B-Genome Specific High Copy hAT MITE Families inFrontiers in plant science · 2020Article
- Article
- Variable genome evolution in fungi after transposon-mediated amplification of a housekeeping gene.Mobile DNA · 2019Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The maize transposon Activator (Ac) was the first mobile DNA element to be discovered. Since then, other elements were found that share similarity to Ac, suggesting that it belongs to a transposon superfamily named hAT after hobo from Drosophila, Ac from maize, and Tam3 from snapdragon. We addressed the structure and evolution of hAT elements by developing new tools for transposon mining and searching the public sequence databases for the hallmarks of hAT elements, namely the transposase and short terminal inverted repeats (TIRs) flanked by 8-bp host duplications. We found 147 hAT-related sequences in plants, animals, and fungi. Six conserved blocks could be identified in the transposase of most hAT elements. A total of 41 hAT sequences were flanked by TIRs and 8-bp host duplications and, out of these, 34 sequences had TIRs similar to the consensus determined in this work, suggesting that they are active or recently active transposons. Phylogenetic analysis and clustering of hAT sequences suggest that the hAT superfamily is very ancient, probably predating the plant-fungi-animal separation, and that, unlike previously proposed, there is no evidence that horizontal gene transfer was involved in the evolution of hAT elements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.