ArticleAntimicrobial agents and chemotherapy2001
Mutation in the DNA gyrase A Gene of Escherichia coli that expands the quinolone resistance-determining region.
Article in Antimicrobial agents and chemotherapy, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Asymmetric envelope surface disposition of secreted protein YjbI controls bimodal antibiotic susceptibilities in C. crescentus.The EMBO journal · 2026Article
- Proteomic Insights into Bacterial Responses to Antibiotics: A Narrative Review.International journal of molecular sciences · 2025Review
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- Reactive oxygen species accelerateiScience · 2023Article
- Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases ofAntibiotics (Basel, Switzerland) · 2021Review
- Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance.Molecules (Basel, Switzerland) · 2020Review
- Antibiotic Resistance Among UropathogenicPolish journal of microbiology · 2019Review
- Article
- High frequency of mutations inIranian journal of basic medical sciences · 2018Article
- The use of SWATH to analyse the dynamic changes of bacterial proteome of carbapanemase-producing Escherichia coli under antibiotic pressure.Scientific reports · 2018Article
- Functional Characterization of the DNA Gyrases in Fluoroquinolone-Resistant Mutants of Francisella novicida.Antimicrobial agents and chemotherapy · 2017Article
- DNA Gyrase Is the Target for the Quinolone Drug Ciprofloxacin in Arabidopsis thaliana.The Journal of biological chemistry · 2016Article
- DNA Topoisomerases.EcoSal Plus · 2015Review
- Clinical importance and epidemiology of quinolone resistance.Infection & chemotherapy · 2014Review
- Article
- Article
- Multiple resistance mechanisms acting in unison in an Escherichia coli clinical isolate.Current microbiology · 2013Article
- Article
- Plasmid-mediated quinolone resistance (PMQR) and mutations in the topoisomerase genes of Salmonella enterica strains from Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2013Article
- Role of the MexEF-OprN efflux system in low-level resistance of Pseudomonas aeruginosa to ciprofloxacin.Antimicrobial agents and chemotherapy · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In three Escherichia coli mutants, a change (Ala-51 to Val) in the gyrase A protein outside the standard quinolone resistance-determining region (QRDR) lowered the level of quinolone susceptibility more than changes at amino acids 67, 82, 84, and 106 did. Revision of the QRDR to include amino acid 51 is indicated.
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Registered trials
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