Evidence map›Paper›PMID 11450659›Full record

ReviewThe New England journal of medicine2001

High-altitude illness.

P H Hackett, R C Roach

5 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in The New England journal of medicine, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 347 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
347citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01519544 nacompletednot on this mapstarted 2012, after this paper: background citation

Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.

TypeinterventionalSponsorMassachusetts General HospitalRan2012 to 2015Enrolled34ConditionsHigh-altitude Sleep DisturbanceArmsTemazepam, Acetazolamide
NCT01522326 nacompletednot on this mapstarted 2012, after this paper: background citation

Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen

TypeinterventionalSponsorMassachusetts General HospitalRan2012 to 2017Enrolled300ConditionsAcute Mountain Sickness, High Altitude HeadacheArmsIbuprofen, Metoclopramide
NCT01536288 phase2completednot on this mapstarted 2010, after this paper: background citation

Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness.

TypeinterventionalSponsorChang Gung Memorial HospitalRan2010 to 2011Enrolled125ConditionsAcute Mountain Sickness, Environmental IllnessArmsRhodiola crenulata, placebo
NCT03828474 phase1completednot on this mapstarted 2019, after this paper: background citation

Sickness Evaluation at Altitude With Acetazolamide at Relative Doses

TypeinterventionalSponsorStanford UniversityRan2019 to 2019Enrolled108ConditionsAcute Mountain SicknessArmsAcetazolamide Pill
NCT05167357 nacompletednot on this mapstarted 2021, after this paper: background citation

Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19

TypeinterventionalSponsorInstitut de Formation et de Recherche en Médecine de MontagneRan2021 to 2021Enrolled68ConditionsCovid19, SARS-CoV2 Infection, Hypoxia, AltitudeArmsCOVID19
3 · Its place in the literature

Who cites it

347 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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287 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

P H HackettDivision of Emergency Medicine, University of Colorado Health Sciences Center, Denver, USA. hackett@ismmed.org
R C Roach

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Altitude SicknessAcetazolamideBrain EdemaCalcium Channel BlockersDiagnosis, DifferentialDiureticsHumansNifedipineOxygenPulmonary EdemaRisk FactorsAcetazolamideCalcium Channel BlockersDiureticsNifedipineOxygen

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.