ArticleAnalytical biochemistry2001
Evaluation of two synthetic glucose probes for fluorescence-lifetime-based sensing.
Article in Analytical biochemistry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 80 citations in OpenAlex.
- Review
- Analysis of glucose concentrations in blood solutions using FTIR and Raman spectroscopy methods.Biomedical optics express · 2025Article
- Dithiane Based Boronic Acid as a Carbohydrate Sensor in an Aqueous Solution at pH 7.5: Theoretical and Experimental Approach.Journal of fluorescence · 2021Article
- Self-grafting copper oxide nanoparticles show a strong enhancement of their anti-algal and anti-yeast action.Nanoscale advances · 2019Article
- The Progress of Glucose Monitoring-A Review of Invasive to Minimally and Non-Invasive Techniques, Devices and Sensors.Sensors (Basel, Switzerland) · 2019Review
- Fluorescence intensity- and lifetime-based glucose sensing using glucose/galactose-binding protein.Journal of diabetes science and technology · 2013Review
- Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding.Chemistry Central journal · 2011Article
- Nanogold plasmon resonance-based glucose sensing. 2. Wavelength-ratiometric resonance light scattering.Analytical chemistry · 2005Article
- Article
- A glucose-sensing contact lens: from bench top to patient.Current opinion in biotechnology · 2005Review
- A wavelength-ratiometric fluoride-sensitive probe based on the quinolinium nucleus and boronic acid moiety.Sensors and actuators. B, Chemical · 2005Article
- Cyanide-sensitive fluorescent probes.Dyes and pigments : an international journal · 2005Article
- OPHTHALMIC GLUCOSE MONITORING USING DISPOSABLE CONTACT LENSES.Reviews in fluorescence · 2005Article
- Wavelength-ratiometric probes for the selective detection of fluoride based on the 6-aminoquinolinium nucleus and boronic acid moiety.Journal of fluorescence · 2004Article
- Fluorescence glucose detection: advances toward the ideal in vivo biosensor.Journal of fluorescence · 2004Review
- Ophthalmic glucose monitoring using disposable contact lenses--a review.Journal of fluorescence · 2004Review
- Time-resolved fluorescent imaging of glucose.Journal of fluorescence · 2004Article
- Boronic acid based modular fluorescent sensors for glucose.Journal of fluorescence · 2004Article
- Ophthalmic glucose sensing: a novel monosaccharide sensing disposable and colorless contact lens.The Analyst · 2004Article
- Noninvasive continuous monitoring of physiological glucose using a monosaccharide-sensing contact lens.Analytical chemistry · 2004Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
We evaluated two anthracene derivatives with covalently attached boronic acid groups for fluorescence-lifetime-based sensing of glucose. These anthracene derivatives also contained alkyl amino groups, which quenched the anthracene emission by photo-induced electron transfer. Both anthracene derivatives displayed increased intensities and lifetime in the presence of glucose, as seen from the frequency-domain measurements. A fluorescence lifetime change from 9.8 to 12.4 and 5.7 to 11.8 ns is observed, after the addition of glucose, for the anthracene substituted with one and two boronic acid groups, respectively. This results in a change in the phase angle up to 15 degrees and 30 degrees and in the modulation up to 12 and 25% at 30 MHz for these compounds, respectively. Titration curves in the presence of BSA and micelles are also presented to show the potential interferences from biomolecules. Dissociation constants were evaluated for both compounds, and association with glucose was found to be reversible. Importantly, the apparent glucose binding constants are about 5- to 10-fold smaller with phase, modulation, or mean lifetime than with intensities measurements, shifting the glucose-sensitive range to physiological values. Combining these results and the use of a simple UV-LED as excitation source, the results show an interesting potential of these two compounds in the development of lifetime base devices using synthetic probes for glucose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.