ArticleJournal of virology2001
N-terminal domain of Borna disease virus G (p56) protein is sufficient for virus receptor recognition and cell entry.
Article in Journal of virology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 70 citations in OpenAlex.
- Article
- Review
- Avian Bornavirus Research-A Comprehensive Review.Viruses · 2022Review
- Analysis of VSV pseudotype virus infection mediated by rubella virus envelope proteins.Scientific reports · 2017Article
- Surface glycoprotein of Borna disease virus mediates virus spread from cell to cell.Cellular microbiology · 2016Article
- Borna disease virus possesses an NF-ĸB inhibitory sequence in the nucleoprotein gene.Scientific reports · 2015Article
- Role of DC-SIGN in Lassa virus entry into human dendritic cells.Journal of virology · 2013Article
- Comprehensive analysis of endogenous bornavirus-like elements in eukaryote genomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- A novel borna disease virus vector system that stably expresses foreign proteins from an intercistronic noncoding region.Journal of virology · 2011Article
- Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Development and Applications of VSV Vectors Based on Cell Tropism.Frontiers in microbiology · 2011Article
- Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines.Journal of virological methods · 2010Article
- A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury.Gene therapy · 2010Article
- Identification of host factors involved in borna disease virus cell entry through a small interfering RNA functional genetic screen.Journal of virology · 2010Article
- Molecular chaperone BiP interacts with Borna disease virus glycoprotein at the cell surface.Journal of virology · 2009Article
- Cell entry of Borna disease virus follows a clathrin-mediated endocytosis pathway that requires Rab5 and microtubules.Journal of virology · 2009Article
- Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (gamma penetrene).Virology journal · 2009Article
- Borna disease virus requires cholesterol in both cellular membrane and viral envelope for efficient cell entry.Journal of virology · 2009Article
- Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers.Virology · 2008Article
- Cellular entry of lymphocytic choriomeningitis virus.Journal of virology · 2008Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Borna disease virus (BDV) surface glycoprotein (GP) (p56) has a predicted molecular mass of 56 kDa. Due to extensive posttranslational glycosylation the protein migrates as a polypeptide of 84 kDa (gp84). The processing of gp84 by the cellular protease furin generates gp43, which corresponds to the C-terminal part of gp84. Both gp84 and gp43 have been implicated in viral entry involving receptor-mediated endocytosis and pH-dependent fusion. We have investigated the domains of BDV p56 involved in virus entry. For this, we used a pseudotype approach based on a recently developed recombinant vesicular stomatitis virus (VSV) in which the gene for green fluorescent protein was substituted for the VSV G protein gene (VSV Delta G*). Complementation of VSV Delta G* with BDV p56 resulted in infectious VSV Delta G* pseudotypes that contained both BDV gp84 and gp43. BDV-VSV chimeric GPs that contained the N-terminal 244 amino acids of BDV p56 and amino acids 421 to 511 of VSV G protein were efficiently incorporated into VSV Delta G* particles, and the resulting pseudotype virions were neutralized by BDV-specific antiserum. These findings indicate that the N-terminal part of BDV p56 is sufficient for receptor recognition and virus entry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.