Evidence map›Paper›PMID 11435411›Full record

ArticleGenome research2001

An enhanced linkage map of the sheep genome comprising more than 1000 loci.

J F Maddox, K P Davies, A M Crawford, D J Hulme, D Vaiman, E P Cribiu, B A Freking, K J Beh, N E Cockett, N Kang and 24 more

Abstract readComparative Study
In one paragraph

Article in Genome research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Review
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  16. Article
  17. Advanced comparative cytogenetic analysis of X chromosomes in river buffalo, cattle, sheep, and human.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012
    Article
  18. Article
  19. Article
  20. Molecular evidence for fat-tailed sheep domestication.Tropical animal health and production · 2011
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

J F MaddoxCentre for Animal Biotechnology (CAB), The University of Melbourne, Parkville 3052, Australia. jillm@rubens.its.unimelb.edu.au
K P Davies
A M Crawford
D J Hulme
D Vaiman
E P Cribiu
B A Freking
K J Beh
N E Cockett
N Kang
C D Riffkin
R Drinkwater
S S Moore
K G Dodds
J M Lumsden
T C van Stijn
S H Phua
D L Adelson
H R Burkin
J E Broom
J Buitkamp
L Cambridge
W T Cushwa
E Gerard
S M Galloway
B Harrison
R J Hawken
S Hiendleder
H M Henry
J F Medrano
K A Paterson
L Schibler
R T Stone
B van Hest

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A medium-density linkage map of the ovine genome has been developed. Marker data for 550 new loci were generated and merged with the previous sheep linkage map. The new map comprises 1093 markers representing 1062 unique loci (941 anonymous loci, 121 genes) and spans 3500 cM (sex-averaged) for the autosomes and 132 cM (female) on the X chromosome. There is an average spacing of 3.4 cM between autosomal loci and 8.3 cM between highly polymorphic [polymorphic information content (PIC) > or = 0.7] autosomal loci. The largest gap between markers is 32.5 cM, and the number of gaps of > 20 cM between loci, or regions where loci are missing from chromosome ends, has been reduced from 40 in the previous map to 6. Five hundred and seventy-three of the loci can be ordered on a framework map with odds of > 1000 : 1. The sheep linkage map contains strong links to both the cattle and goat maps. Five hundred and seventy-two of the loci positioned on the sheep linkage map have also been mapped by linkage analysis in cattle, and 209 of the loci mapped on the sheep linkage map have also been placed on the goat linkage map. Inspection of ruminant linkage maps indicates that the genomic coverage by the current sheep linkage map is comparable to that of the available cattle maps. The sheep map provides a valuable resource to the international sheep, cattle, and goat gene mapping community.

Indexed as

Genetic LinkageGenomeAnimalsCattleChromosome MappingFemaleGenetic MarkersGenotypeMaleMeiosisMicrosatellite RepeatsMinisatellite RepeatsPolymorphism, Restriction Fragment LengthSheepGenetic Markers

Identifiers

PMID11435411
PMCPMC311104

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.