ArticleGlycoconjugate journal
Progress in deciphering the information content of the 'glycome'--a crescendo in the closing years of the millennium.
Article in Glycoconjugate journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 72 citations in OpenAlex.
- Application of Lectin Microarrays for Biomarker Discovery.ChemistryOpen · 2020Review
- Lectin engineering: the possible and the actual.Interface focus · 2019Review
- Determination of carbohydrate structure recognized by prostate-specific F77 monoclonal antibody through expression analysis of glycosyltransferase genes.The Journal of biological chemistry · 2014Article
- Glyco-epitope Diversity: An Evolving Area of Glycomics Research and Biomarker Discovery.Journal of proteomics & bioinformatics · 2014Article
- Neutralization of B. anthracis toxins during ex vivo phagocytosis.Glycoconjugate journal · 2013Article
- Versatile high resolution oligosaccharide microarrays for plant glycobiology and cell wall research.The Journal of biological chemistry · 2012Article
- Transcriptome and proteome research in veterinary science: what is possible and what questions can be asked?TheScientificWorldJournal · 2012Review
- Glycoconjugates prevent B. anthracis toxin-induced cell death through binding while activating macrophages.Glycoconjugate journal · 2012Article
- Protein biomarkers in cancer: natural glycoprotein microarray approaches.Current opinion in molecular therapeutics · 2008Review
- Polymeric glycoconjugates protect and activate macrophages to promote killing of Bacillus cereus spores during phagocytosis.Glycoconjugate journal · 2008Article
- Photons to illuminate the universe of sugar diversity through bioarrays.Glycoconjugate journal · 2008Review
- Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase.Molecular and cellular biochemistry · 2004Article
- Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition.The Journal of cell biology · 2004Article
- Plant proteomics: BLASTing out of a MudPIT.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- An appreciation of Elvin A. Kabat (1914-2000): scientist, educator and a founder of modern carbohydrate biology.Glycoconjugate journalArticle
- Protein-bound carbohydrates on cell-surface as targets of recognition: an odyssey in understanding them.Glycoconjugate journalArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The closing years of the second millennium have been uplifting for carbohydrate biology. Optimism that oligosaccharide sequences are bearers of crucial biological information has been borne out by the constellation of efforts of carbohydrate chemists, biochemists, immunochemists, and cell- and molecular biologists. The direct involvement of specific oligosaccharide sequences in protein targeting and folding, and in mechanisms of infection, inflammation and immunity is now unquestioned. With the emergence of families of proteins with carbohydrate-binding activities, assignments of information content for defined oligosaccharide sequences will become more common, but the pinpointing and elucidation of the bioactive domains on oligosaccharides will continue to pose challenges even to the most experienced carbohydrate biologists. The neoglycolipid technology incorporates some of the key requirements for this challenge: namely the resolution of complex glycan mixtures, and ligand binding coupled with sequence determination by mass spectrometry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.