ReviewMolecular neurobiology
Spinal-Cord plasticity: independent and interactive effects of neuromodulator and activity-dependent plasticity.
Review in Molecular neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Human-induced pluripotent stem cell-derived neural stem/progenitor cell ex vivo gene therapy with synaptic organizer CPTX for spinal cord injury.Stem cell reports · 2024Article
- Article
- EPO-releasing neural precursor cells promote axonal regeneration and recovery of function in spinal cord traumatic injury.Restorative neurology and neuroscience · 2017Article
- Distinct and developmentally regulated activity-dependent plasticity at descending glutamatergic synapses on flexor and extensor motoneurons.Scientific reports · 2016Article
- A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.PloS one · 2015Article
- Neuromodulation of neurons and synapses.Current opinion in neurobiology · 2014Review
- Neuromodulator-evoked synaptic metaplasticity within a central pattern generator network.Journal of neurophysiology · 2012Article
- Role of type-specific neuron properties in a spinal cord motor network.Journal of computational neuroscience · 2007Article
- Complexities and uncertainties of neuronal network function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Review
- Metaplastic facilitation and ultrastructural changes in synaptic properties are associated with long-term modulation of the lamprey locomotor network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Activity-dependent feedforward inhibition modulates synaptic transmission in a spinal locomotor network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Spike width reduction modifies the dynamics of short-term depression at a central synapse in the locust.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Variable properties in a single class of excitatory spinal synapse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Gating and braking of short- and long-term modulatory effects by interactions between colocalized neuromodulators.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasticity is one of the most extensively studied aspects in neuroscience. Interest in it has primarily been related to its proposed role in learning and memory and its relevance to adaptive changes following injury. Plasticity can be evoked by changes in molecular, cellular, and synaptic properties, either as a result of activity-dependent effects, or by relatively slow-acting neuromodulatory transmitters. In addition, it is increasingly recognized that the plasticity evoked by these individual effects can be altered by previous inputs and is thus itself plastic. Here, I will review studies in the lamprey spinal cord that have examined individual and interactive activity-dependent and neuromodulator-mediated plasticity. The results show that activity-dependent and neuromodulator-mediated plasticity evoke neuron-and synapse-specific effects at different levels in the spinal cord, and that interactions within and between these effects can evoke dynamic changes in cellular, synaptic, and network plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.