ReviewMolecular neurobiology
Regulation of feeding-associated peptides and receptors by nicotine.
Review in Molecular neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Maternal smoking during pregnancy and child overweight: systematic review and meta-analysis.International journal of obesity (2005) · 2008Pooled it
- The Association of Serum Total Peptide YY (PYY) with Obesity and Body Fat Measures in the CODING Study.PloS one · 2014Trial
- DRD4 48 bp VNTR but not 5-HT 2C Cys23Ser receptor polymorphism is related to antipsychotic-induced weight gain.The pharmacogenomics journal · 2009Trial
- Acute nicotine intake increases feeding behavior through decreasing glucagon signaling in dependent male and female rats.Hormones and behavior · 2024Article
- Maternal smoking during pregnancy links to childhood blood pressure through birth weight and body mass index: NHANES 1999-2018.Journal of human hypertension · 2024Article
- Phytochemicals derived fromFrontiers in pharmacology · 2024Review
- Substitutability of nicotine and sucrose in rats: A behavioral economic analysis.Pharmacology, biochemistry, and behavior · 2023Article
- Association between maternal e-cigarette use during pregnancy and low gestational weight gain.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Article
- Prenatal tobacco and cannabis co-exposure and offspring obesity development from birth to mid-childhood.Pediatric obesity · 2023Article
- The Effect of Smoking Cessation on Body Weight and Other Metabolic Parameters with Focus on People with Type 2 Diabetes Mellitus.International journal of environmental research and public health · 2022Review
- Cardiometabolic Morbidity and Mortality with Smoking Cessation, Review of Recommendations for People with Diabetes and Obesity.Current diabetes reports · 2020Review
- Maternal smoking during pregnancy and offspring body composition in adulthood: Results from two birth cohort studies.BMJ open · 2019Article
- Pharmacological Effects and Regulatory Mechanisms of Tobacco Smoking Effects on Food Intake and Weight Control.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2018Review
- Involvement of cholinergic mechanisms in the behavioral effects of dietary fat consumption.Brain research · 2012Article
- Maternal and Early Childhood Risk Factors for Overweight and Obesity among Low-Income Predominantly Black Children at Age Five Years: A Prospective Cohort Study.Journal of obesity · 2012Article
- Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: similarities and differences.Journal of neurophysiology · 2011Article
- Circulating leptin levels are associated with increased craving to smoke in abstinent smokers.Pharmacology, biochemistry, and behavior · 2011Article
- Neuropeptide Y Y2 receptor in health and disease.British journal of pharmacology · 2008Review
- Coronary Heart Disease (CHD) Risk Factors and Metabolic Syndrome in HIV-Positive Drug Users in Miami.American journal of infectious diseases · 2006Article
- Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Although numerous epidemiological studies have provided convincing evidence for the inverse association between tobacco smoking and body weight, the molecular mechanisms underlying this relationship are not well-understood. Nicotine, as a potent secretagogue, could be expected to influence the levels and expression of many classes of neurotransmitters, as well as of cell-membrane constituents linked to neurotransmission, including signal transducers and related effectors. A potentially major group of candidate molecules that could be involved in feeding-related actions of nicotine are the numerous neuropeptides and peptide hormones shown in the past two decades to regulate food intake and energy expenditure. These could include neuropeptide Y (NPY), orexins, leptins, and uncoupling proteins (UCPs). Some of these peptides were already shown to respond to nicotine treatment in terms of regulation of levels and of activity at the level of cell-membrane receptors. The primary objective of this review is to summarize our current understanding of the regulatory effects of nicotine on the food intake and energy expenditure as related to the expression levels of leptin, NPY, orexin, uncoupling proteins, and of NPY and orexin receptors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.