Evidence map›Paper›PMID 11414276›Full record

ReviewMolecular neurobiology

Control of Na+ spike backpropagation by intracellular signaling in the pyramidal neuron dendrites.

H Tsubokawa

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Timing is not Everything: Neuromodulation Opens the STDP Gate.Frontiers in synaptic neuroscience · 2010
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

H TsubokawaSection of Brain Information, Center for Brain Experiment, National Institute for Physiological Sciences, Okazaki, Japan.
National Institute for Physiological Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integrative function of neurons depends on the somato-dendritic distribution and properties of voltage-gated ion channels. Sodium, potassium, calcium, and hyperpolarization-activated cyclic nucleotide-gated K+ (HCN) channels expressed in the dendrites can be modulated by a number of neurotransmitters and second-messenger systems. For example, activation of protein kinases leads to an increase in dendritic excitability by removing a slow inactivation of Na+ channels and decreasing the activity of transient K+ channels in the apical dendrites of hippocampal pyramidal neurons. Consequently, action potentials propagating along the dendrites can be modified significantly by a variety of neuromodulatory synaptic inputs.

Indexed as

AcetylcholineAction PotentialsAnimalsBrain ChemistryCalcium ChannelsCyclic Nucleotide-Gated Cation ChannelsDendritesForecastingGTP-Binding ProteinsHumansHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIon Channel GatingIon ChannelsIon TransportModels, NeurologicalNerve Tissue ProteinsAcetylcholineCalcium ChannelsCyclic Nucleotide-Gated Cation ChannelsGTP-Binding ProteinsHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIon ChannelsNerve Tissue ProteinsNeurotransmitter AgentsNorepinephrinePotassium ChannelsSerotoninSodiumSodium Channels

Identifiers

PMID11414276
OpenAlexW1984667286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.