ArticleJournal of epidemiology and community health2001
The incidence of childhood leukaemia around the La Hague nuclear waste reprocessing plant (France): a survey for the years 1978-1998.
Article in Journal of epidemiology and community health, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Gender Differences in Oxidative Stress in Relation to Cancer Susceptibility and Survival.Antioxidants (Basel, Switzerland) · 2023Review
- Radiation-induced Non-targeted Effect and Carcinogenesis; Implications in Clinical Radiotherapy.Journal of biomedical physics & engineering · 2018Article
- Emerging Environmental Justice Issues in Nuclear Power and Radioactive Contamination.International journal of environmental research and public health · 2016Article
- Comment on 'Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay': premature all-clear for nuclear power.British journal of cancer · 2015Article
- Epidemiological evidence of childhood leukaemia around nuclear power plants.Dose-response : a publication of International Hormesis Society · 2014Article
- A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line.BioEssays : news and reviews in molecular, cellular and developmental biology · 2014Article
- Childhood leukaemia, nuclear sites, and population mixing.British journal of cancer · 2011Review
- Temporal trends in childhood leukaemia incidence following exposure to radioactive fallout from atmospheric nuclear weapons testing.Radiation and environmental biophysics · 2010Article
- Commentary: childhood cancer near nuclear power stations.Environmental health : a global access science source · 2009Article
- Incidence of childhood leukaemia in the vicinity of nuclear sites in France, 1990-1998.British journal of cancer · 2004Article
- The cancer epidemiology of radiation.Oncogene · 2004Review
- Population mixing and leukaemia in young people around the La Hague nuclear waste reprocessing plant.British journal of cancer · 2002Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA previous study has suggested an increased incidence rate of leukaemia from 1978 to 1992 in people aged 0 to 24 years and living in the vicinity of the La Hague nuclear waste reprocessing plant without considering age and cytological type.
settingThe Nord Cotentin region (France) and the island of Alderney (United Kingdom). STUDY
objectiveTo describe the occurrence of leukaemia for each age group and cytological type from 1978 to 1998 in the same area, using accurate reference incidence rates and adequate estimation of the at risk population.
designA geographical study of incidence using three zones defined according to their distance from the site (0 to 10 km: Beaumont-Hague electoral ward, 10 to 20 km and 20 to 35 km) has been conducted. The risk of leukaemia was estimated from the standardised incidence ratio (SIR) of the number of cases observed to the number expected. Exact 95% confidence intervals (CI) have been computed.
participantsAll people under the age of 25 years living in the study region between 1978 and 1998. MAIN
resultsThe observed number of cases of leukaemia in the study region as a whole was consistent with the expected value (SIR=1.03; 95%CI: 0.73, 1.41). No cases were observed on Alderney. The SIR in the Beaumont-Hague electoral ward was 2.17 (95%CI: 0.71, 5.07). The highest SIR was observed in the 5 to 9 years age group (SIR=6.38; 95%CI: 1.32, 18.65). This consists in acute lymphoblastic leukaemia cases.
conclusionThis study indicates an increased incidence of leukaemia in the area situated at less than 10 km from the plant. Monitoring and further investigations should be targeted at acute lymphoblastic leukaemia occurring during the childhood incidence peak (before 10 years) in children living near the La Hague site and may be other nuclear reprocessing plants.
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